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Invest Ophthalmol Vis Sci 2003;44: E-Abstract 5016.
© 2003 ARVO

5016—B675

Short-Wavelength Automated Perimetry (SWAP) and Retrobulbar Hemodynamics in Age-Related Maculopathy

A. Weber1, A. Remky1, A. Cordes1 and O. Arend1

1 RWTH Aachen, Aachen, Germany

Commercial Relationships: A. Weber, None; A. Remky, None; A. Cordes, None; O. Arend, None.

Abstract

Purpose: To investigate the correlation between visual function assessed by short-wavelength automated perimetry and retrobulbar flow velocities assessed with Color Doppler Imaging (CDI) in patients with age-related maculopathy (ARM).
Methods: In a prospective study 37 patients with ARM (mean age: 74 ± 7 years, mean visual acuity: 0.67) were included. Short-wavelength automated perimetry was performed in the central 10°- field with a conventional perimeter (Humphrey field analyzer, prg. 10-2). In the ophthalmic artery (OA), nasal and temporal short ciliary arteries (PCA), and central retinal artery (CRA) flow velocities (peak systolic and end-diastolic velocities) and resistive indices were measured with Color Doppler Imaging (Siemens Sonoline Sienna).
Results: The resistive index of the CRA was significantly correlated with the mean short-wavelength sensitivity (r = -0.42, p = 0.008). All other parameters were not correlated to mean sensitivity.
Conclusions: Decreased short-wavelength sensitivity is known to be a functional risk factor for exudative age-related macular degeneration (AMD). In this study we found a correlation of downstream resistance of the central artery and visual function already in ARM. These results suggest the possible impact of disturbed ocular microcirculation in the pathogenesis of AMD.

Keywords: age-related macular degeneration • blood supply • clinical (human) or epidemiologic studies: ris

© 2003, The Association for Research in Vision and Ophthalmology, Inc., all rights reserved. For permission to reproduce any part of this abstract, contact the ARVO Office at arvo{at}arvo.org.




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