Immunology and Microbiology

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Methods April 2024

PTVR – A software in Python to make virtual reality experiments easier to build and more reproducible

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Eric Castet; Jérémy Termoz-Masson; Sebastian Vizcay; Johanna Delachambre; Vasiliki Myrodia; Carlos Aguilar; Frédéric Matonti; Pierre Kornprobst
TAGS: script, software, virtual reality, vision, research personnel
Journal of Vision. 2024; 24(4):19. https://doi.org/10.1167/jov.24.4.19

Cornea April 2024

Mitochondrial DNA-Activated cGAS-STING Signaling in Environmental Dry Eye

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Xiying Tan; Qianqian Chen; Zhonghua Chen; Zhenzhen Sun; Wei Chen; Ruifen Wei
TAGS: dna, dna, mitochondrial, dry eye syndromes, mitochondria, signal transduction, mice, cytoplasm
Invest. Ophthalmol. Vis. Sci.. 2024; 65(4):33. https://doi.org/10.1167/iovs.65.4.33

Includes: Supplemental Content

Retinal Cell Biology April 2024

Autophagy and Exocytosis of Lipofuscin Into the Basolateral Extracellular Space of Human Retinal Pigment Epithelium From Fetal Development to Adolescence

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Saeed Shahhossein-Dastjerdi; Mark E. Koina; George Fatseas; Frank Arfuso; Tailoi Chan-Ling
TAGS: adolescent, autophagy, exocytosis, extracellular space, eye, fetal development, fetus, lipofuscin, retinal pigment cell, retinal pigment epithelium
Invest. Ophthalmol. Vis. Sci.. 2024; 65(4):32. https://doi.org/10.1167/iovs.65.4.32

Immunology and Microbiology April 2024

Aspergillus fumigatus Hypoxia Adaptation Is Critical for the Establishment of Fungal Keratitis

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Jorge D. Lightfoot; Emily M. Adams; Manali M. Kamath; Becca L. Wells; Kevin K. Fuller
TAGS: cornea, fungal keratitis, hypoxia, aspergillus fumigatus
Invest. Ophthalmol. Vis. Sci.. 2024; 65(4):31. https://doi.org/10.1167/iovs.65.4.31

Includes: Supplemental Content

Retina April 2024

Photoreceptor Integrity in MEWDS: Longitudinal Structure-Function Correlations

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Maria Vittoria Cicinelli; Giovanni Montesano; Alessandro Berni; Pierluigi Scandale; Giovanni Ometto; Ugo Introini; Maurizio Battaglia Parodi; Francesco Bandello; Elisabetta Miserocchi; Alessandro Marchese
TAGS: multiple evanescent white dot syndrome, personal integrity, photoreceptors, spectral domain-optical coherence tomography
Invest. Ophthalmol. Vis. Sci.. 2024; 65(4):28. https://doi.org/10.1167/iovs.65.4.28

Includes: Supplemental Content

Cornea April 2024

Endoplasmic Reticulum Stress and Unfolded Protein Response in Vernal Keratoconjunctivitis

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Andrea Leonardi; Alice Donato; Umberto Rosani; Antonino Di Stefano; Fabiano Cavarzeran; Paola Brun
TAGS: conjunctiva, endoplasmic reticulum, keratoconjunctivitis, vernal, stress, unfolded protein response, apoptosis, genes, autophagy, cell culture techniques
Invest. Ophthalmol. Vis. Sci.. 2024; 65(4):23. https://doi.org/10.1167/iovs.65.4.23

Includes: Supplemental Content

Retina April 2024

Role of Hsa_circ_0000880 in the Regulation of High Glucose-Induced Apoptosis of Retinal Microvascular Endothelial Cells

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Jiawei Wang; Nannan Yang; Wanna Li; Han Zhang; Jianqiao Li
TAGS: apoptosis, circular rna, endothelial cells, glucose, epiretinal membrane, regulation
Trans. Vis. Sci. Tech.. 2024; 13(4):12. https://doi.org/10.1167/tvst.13.4.12

Artificial Intelligence April 2024

Enhancing Retinal Fundus Image Quality Assessment With Swin-Transformer–Based Learning Across Multiple Color-Spaces

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Chengcheng Huang; Yukang Jiang; Xiaochun Yang; Chiyu Wei; Hongyu Chen; Weixue Xiong; Henghui Lin; Xueqin Wang; Ting Tian; Haizhu Tan
TAGS: color, datasets, image quality, learning
Trans. Vis. Sci. Tech.. 2024; 13(4):8. https://doi.org/10.1167/tvst.13.4.8

Includes: Supplemental Content

Anatomy and Pathology/Oncology April 2024

Expression of Collagen XIII in Tissues of the Thyroid and Orbit With Relevance to Thyroid-Associated Ophthalmopathy

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Oula Norman; Tuuli Vornanen; Hanna Franssila; Johanna Liinamaa; Elina Karvonen; Tommi Kotkavaara; Vesa-Matti Pohjanen; Ritva Ylikärppä; Taina Pihlajaniemi; Merja Hurskainen; Anne Heikkinen
TAGS: body tissue, collagen, thyroid, graves' ophthalmopathy, orbit
Invest. Ophthalmol. Vis. Sci.. 2024; 65(4):6. https://doi.org/10.1167/iovs.65.4.6

Includes: Supplemental Content

Lens April 2024

Dysregulation of Autophagy Occurs During Congenital Cataract Development in βA3ΔG91 Mice

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Akosua K. Boateng; Roy Joseph; Om P. Srivastava
TAGS: autophagy, crystallins, lens (device), lens, crystalline, mice, congenital cataract, proteins
Invest. Ophthalmol. Vis. Sci.. 2024; 65(4):4. https://doi.org/10.1167/iovs.65.4.4

Includes: Supplemental Content

Anatomy and Pathology/Oncology March 2024

scRNA-Seq: First Atlas and Cellular Landscape of Lacrimal Sac: Implications in Primary Acquired Nasolacrimal Duct Obstruction Pathogenesis

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Wenyue Zhang; Huan Huang; Xueru Liu; Leilei Zhang; Lunhao Li; Yi Ding; Yichuan Xiao; Mohammad Javed Ali; Hao Sun; Caiwen Xiao
TAGS: epithelial cells, genes, lacrimal sac, nasolacrimal duct obstruction, pathogenesis, rna, small cytoplasmic, neutrophils, b-lymphocytes, inflammation, t-lymphocytes
Invest. Ophthalmol. Vis. Sci.. 2024; 65(3):38. https://doi.org/10.1167/iovs.65.3.38

Includes: Supplemental Content

Anatomy and Pathology/Oncology March 2024

IL-6-Driven Autocrine Lactate Promotes Immune Escape of Uveal Melanoma

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Chaoju Gong; Meiling Yang; Huirong Long; Xia Liu; Qing Xu; Lei Qiao; Haibei Dong; Yalu Liu; Suyan Li
TAGS: hla-e antigens, interleukin-6, intraocular melanoma, lactates, programmed cell death 1 ligand 1, proteins, autocrine
Invest. Ophthalmol. Vis. Sci.. 2024; 65(3):37. https://doi.org/10.1167/iovs.65.3.37

Includes: Supplemental Content

Immunology and Microbiology March 2024

Whole Genome Sequencing Highlights the Pathogenic Profile in Nocardia Keratitis

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Xiaoyan Guo; Zijun Zhang; Qiankun Chen; Leying Wang; Xizhan Xu; Zhenyu Wei; Yang Zhang; Kexin Chen; Zhiqun Wang; Xinxin Lu; Qingfeng Liang
TAGS: cornea, genes, keratitis, nocardia, family
Invest. Ophthalmol. Vis. Sci.. 2024; 65(3):26. https://doi.org/10.1167/iovs.65.3.26

Includes: Supplemental Content

Cornea March 2024

Expression of ATP-Binding Cassette Transporter A1 (ABCA1) in Eyelid Tissues and Meibomian Gland Epithelial Cells

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Fang Zheng; Jingjing Su; Jiaoman Wang; Qing Zhan; Mei Su; Sicheng Ding; Wei Li; Ying-Ting Zhu; Ping Guo
TAGS: abca1 gene, body tissue, epithelial cells, eyelid, meibomian gland, membrane transport proteins
Invest. Ophthalmol. Vis. Sci.. 2024; 65(3):24. https://doi.org/10.1167/iovs.65.3.24

Immunology and Microbiology March 2024

Exploring Heparanase Levels in Tears: Insights From Herpes Simplex Virus-1 Keratitis Patients and Animal Studies

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Satyashree Gagan; Agimanailiu Khapuinamai; Divya Kapoor; Pankaj Sharma; Tejabhiram Yadavalli; Joveeta Joseph; Deepak Shukla; Bhupesh Bagga
TAGS: heparanase, herpes simplex infection, human herpesvirus 1, keratitis, mice, mice, inbred c57bl, viruses, simplexvirus, animal testing
Invest. Ophthalmol. Vis. Sci.. 2024; 65(3):7. https://doi.org/10.1167/iovs.65.3.7

Includes: Supplemental Content

Cornea March 2024

Substrate Stiffness Modulates Stemness and Differentiation of Rabbit Corneal Endothelium Through the Paxillin–YAP Pathway

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Shuting Liu; Hua Chen; Huatao Xie; Xin Liu; Mingchang Zhang
TAGS: chronic exertional compartment syndrome, cornea, corneal endothelium, oryctolagus cuniculus, scirrhous adenocarcinoma
Invest. Ophthalmol. Vis. Sci.. 2024; 65(3):15. https://doi.org/10.1167/iovs.65.3.15

Includes: Supplemental Content

Biochemistry and Molecular Biology March 2024

Unraveling the Intraday Variations in the Tear Fluid Proteome

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Garrett Jones; Jeremy Altman; Saleh Ahmed; Tae Jin Lee; Wenbo Zhi; Shruti Sharma; Ashok Sharma
TAGS: proteins, proteome
Invest. Ophthalmol. Vis. Sci.. 2024; 65(3):2. https://doi.org/10.1167/iovs.65.3.2

Includes: Supplemental Content

Cornea February 2024

Ferroptosis as a Potential Therapeutic Target for Reducing Inflammation and Corneal Scarring in Bacterial Keratitis

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Qiankun Chen; Leying Wang; Yuan Wei; Xizhan Xu; Xiaoyan Guo; Qingfeng Liang
TAGS: bacterial keratitis, cicatrix, cornea, ferroptosis, inflammation, mice, iron
Invest. Ophthalmol. Vis. Sci.. 2024; 65(2):29. https://doi.org/10.1167/iovs.65.2.29

Includes: Supplemental Content

Retina February 2024

Histologic and Immunohistochemical Characterization of GA-Like Pathology in the Rat Subretinal Sodium Iodate Model

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Poonam Naik; Rhonda Grebe; Imran A. Bhutto; D. Scott McLeod; Malia M. Edwards
TAGS: atrophic condition of skin, atrophy, eye, immunohistochemistry, injections, iodates, pathology, sodium, tissue membrane, choroid
Trans. Vis. Sci. Tech.. 2024; 13(2):10. https://doi.org/10.1167/tvst.13.2.10

Immunology and Microbiology February 2024

SOX9 Induces Orbital Fibroblast Activation in Thyroid Eye Disease Via MAPK/ERK1/2 Pathway

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Min Zhou; Bingying Lin; Pengsen Wu; Yu Ke; Siyu Huang; Fan Zhang; Xiangqing Hei; Zhen Mao; Xingyi Li; Pengxia Wan; Tingting Chen; Huasheng Yang; Danping Huang
TAGS: fibroblasts, graves' ophthalmopathy, mitogen-activated protein kinases, sox9 gene, fibrosis
Invest. Ophthalmol. Vis. Sci.. 2024; 65(2):25. https://doi.org/10.1167/iovs.65.2.25

Includes: Supplemental Content

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PTVR – A software in Python to make virtual reality experiments easier to build and more reproducible

Mitochondrial DNA-Activated cGAS-STING Signaling in Environmental Dry Eye

Autophagy and Exocytosis of Lipofuscin Into the Basolateral Extracellular Space of Human Retinal Pigment Epithelium From Fetal Development to Adolescence

Aspergillus fumigatus Hypoxia Adaptation Is Critical for the Establishment of Fungal Keratitis

Photoreceptor Integrity in MEWDS: Longitudinal Structure-Function Correlations

Endoplasmic Reticulum Stress and Unfolded Protein Response in Vernal Keratoconjunctivitis

Role of Hsa_circ_0000880 in the Regulation of High Glucose-Induced Apoptosis of Retinal Microvascular Endothelial Cells

Enhancing Retinal Fundus Image Quality Assessment With Swin-Transformer–Based Learning Across Multiple Color-Spaces

Expression of Collagen XIII in Tissues of the Thyroid and Orbit With Relevance to Thyroid-Associated Ophthalmopathy

Dysregulation of Autophagy Occurs During Congenital Cataract Development in βA3ΔG91 Mice

scRNA-Seq: First Atlas and Cellular Landscape of Lacrimal Sac: Implications in Primary Acquired Nasolacrimal Duct Obstruction Pathogenesis

IL-6-Driven Autocrine Lactate Promotes Immune Escape of Uveal Melanoma

Whole Genome Sequencing Highlights the Pathogenic Profile in Nocardia Keratitis

Expression of ATP-Binding Cassette Transporter A1 (ABCA1) in Eyelid Tissues and Meibomian Gland Epithelial Cells

Exploring Heparanase Levels in Tears: Insights From Herpes Simplex Virus-1 Keratitis Patients and Animal Studies

Substrate Stiffness Modulates Stemness and Differentiation of Rabbit Corneal Endothelium Through the Paxillin–YAP Pathway

Unraveling the Intraday Variations in the Tear Fluid Proteome

Ferroptosis as a Potential Therapeutic Target for Reducing Inflammation and Corneal Scarring in Bacterial Keratitis

Histologic and Immunohistochemical Characterization of GA-Like Pathology in the Rat Subretinal Sodium Iodate Model

SOX9 Induces Orbital Fibroblast Activation in Thyroid Eye Disease Via MAPK/ERK1/2 Pathway

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