Clinical and Epidemiologic Research

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Genetics May 2018

Family-Based Genome-Wide Association Study of South Indian Pedigrees Supports WNT7B as a Central Corneal Thickness Locus

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Bao Jian Fan; Xueli Chen; Nisha Sondhi; P. Ferdinamarie Sharmila; Nagasamy Soumittra; Sarangapani Sripriya; Srinivasan Sacikala; Rashima Asokan; David S. Friedman; Louis R. Pasquale; X. Raymond Gao; Lingam Vijaya; Jessica Cooke Bailey; Veronique Vitart; Stuart MacGregor; Christopher J. Hammond; Chiea Chuen Khor; Jonathan L. Haines; Ronnie George; Janey L. Wiggs; for the Mexican American Glaucoma Genetic Study; International Glaucoma Genetics Consortium; and NEIGHBORHOOD Consortium
TAGS: cohort studies, family, genetic pedigree, single nucleotide polymorphism, cornea, genome-wide association study
Invest. Ophthalmol. Vis. Sci.. 2018; 59(6):2495-2502. doi: 10.1167/iovs.17-23536

Includes: Supplemental Content

Clinical and Epidemiologic Research May 2018

Clinical Outcomes of Fixed Versus As-Needed Use of Artificial Tears in Dry Eye Disease: A 6-Week, Observer-Masked Phase 4 Clinical Trial

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Penny Asbell; Algis J. Vingrys; Jacqueline Tan; Abayomi Ogundele; Laura E. Downie; Gary Jerkins; Lee Shettle
TAGS: phase iv trial, dry eye syndromes, treatment outcome, ocular lubricants
Invest. Ophthalmol. Vis. Sci.. 2018; 59(6):2275-2280. doi: 10.1167/iovs.17-23733

Includes: Supplemental Content

Clinical and Epidemiologic Research April 2018

Direct and Indirect Associations Between Diabetes and Intraocular Pressure: The Singapore Epidemiology of Eye Diseases Study

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Xiao-Yang Luo; Nicholas Y. Q. Tan; Miao-Li Chee; Yuan Shi; Yih-Chung Tham; Tien Yin Wong; Jie Jin Wang; Ching-Yu Cheng
TAGS: diabetes mellitus, diabetes mellitus, type 2, epidemiology, eye diseases, singapore, intraocular pressure
Invest. Ophthalmol. Vis. Sci.. 2018; 59(5):2205-2211. doi: 10.1167/iovs.17-23013

Clinical and Epidemiologic Research April 2018

Long Anterior Lens Zonules and Intraocular Pressure

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Daniel K. Roberts; Tricia L. Newman; Mary Flynn Roberts; Bruce A. Teitelbaum; Janis E. Winters
TAGS: lens, crystalline, eye, intraocular pressure
Invest. Ophthalmol. Vis. Sci.. 2018; 59(5):2015-2023. doi: 10.1167/iovs.17-23705

Includes: Supplemental Content

Clinical and Epidemiologic Research April 2018

The Economic Burden of Visual Impairment and Comorbid Fatigue: A Cost-of-Illness Study (From a Societal Perspective)

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Wouter Schakel; Hilde P. A. van der Aa; Christina Bode; Carel T. J. Hulshof; Ger H. M. B. van Rens; Ruth M. A. van Nispen
TAGS: fatigue, comorbidity, cost of illness, visual impairment, economics
Invest. Ophthalmol. Vis. Sci.. 2018; 59(5):1916-1923. doi: 10.1167/iovs.17-23224

Visual Psychophysics and Physiological Optics April 2018

Consistency of Structure-Function Correlation Between Spatially Scaled Visual Field Stimuli and In Vivo OCT Ganglion Cell Counts

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Nayuta Yoshioka; Barbara Zangerl; Jack Phu; Agnes Y. J. Choi; Sieu K. Khuu; Katherine Masselos; Michael P. Hennessy; Michael Kalloniatis
TAGS: glaucoma, cell count, cohort studies, ganglia, visual fields, photon correlation spectroscopy
Invest. Ophthalmol. Vis. Sci.. 2018; 59(5):1693-1703. doi: 10.1167/iovs.17-23683

Includes: Supplemental Content

Clinical and Epidemiologic Research April 2018

Plasma Concentrations of Lutein and Zeaxanthin, Macular Pigment Optical Density, and Their Associations With Cognitive Performances Among Older Adults

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Soufiane Ajana; Daniela Weber; Catherine Helmer; Bénédicte M. Merle; Wolfgang Stuetz; Jean-François Dartigues; Marie-Bénédicte Rougier; Jean-François Korobelnik; Tilman Grune; Cécile Delcourt; Catherine Féart
TAGS: plasma drug concentration, cognition, lutein, mental processes, optics, plasma, elderly, cognitive ability, macular pigment
Invest. Ophthalmol. Vis. Sci.. 2018; 59(5):1828-1835. doi: 10.1167/iovs.17-22656

Includes: Supplemental Content

Articles March 2018

Towards Standardization of Quantitative Retinal Vascular Parameters: Comparison of SIVA and VAMPIRE Measurements in the Lothian Birth Cohort 1936

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Sarah McGrory; Adele M. Taylor; Enrico Pellegrini; Lucia Ballerini; Mirna Kirin; Fergus N. Doubal; Joanna M. Wardlaw; Alex S. F. Doney; Baljean Dhillon; John M. Starr; Emanuele Trucco; Ian J. Deary; Thomas J. MacGillivray
TAGS: cohort studies, fractals, software, diagnostic imaging, birth, pixel, bland-altman plot
Trans. Vis. Sci. Tech.. 2018; 7(2):12. doi: 10.1167/tvst.7.2.12

Includes: Supplemental Content

Clinical and Epidemiologic Research March 2018

Distribution Pattern of Choroidal Thickness at the Posterior Pole in Chinese Children With Myopia

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Junjie Deng; Xiaoli Li; Jiali Jin; Bo Zhang; Jianfeng Zhu; Haidong Zou; Xun Xu; Jingbo Xie; Ling Wang; Shaopin Zhu; Xiangui He
TAGS: child, myopia, choroid, chinese people, chinese (other dialects)
Invest. Ophthalmol. Vis. Sci.. 2018; 59(3):1577-1586. doi: 10.1167/iovs.17-22748

Articles March 2018

How Many Subjects are Needed for a Visual Field Normative Database? A Comparison of Ground Truth and Bootstrapped Statistics

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Jack Phu; Bang V. Bui; Michael Kalloniatis; Sieu K. Khuu
TAGS: glaucoma, cohort studies, retrospective studies, visual fields
Trans. Vis. Sci. Tech.. 2018; 7(2):1. doi: 10.1167/tvst.7.2.1

Includes: Supplemental Content

Clinical and Epidemiologic Research February 2018

Clinical Age-Specific Seasonal Conjunctivitis Patterns and Their Online Detection in Twitter, Blog, Forum, and Comment Social Media Posts

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Michael S. Deiner; Stephen D. McLeod; James Chodosh; Catherine E. Oldenburg; Cherie A. Fathy; Thomas M. Lietman; Travis C. Porco
TAGS: conjunctivitis, allergic conjunctivitis, electronic medical records, social media
Invest. Ophthalmol. Vis. Sci.. 2018; 59(2):910-920. doi: 10.1167/iovs.17-22818

Includes: Supplemental Content

Clinical and Epidemiologic Research February 2018

Use of the Posterior/Anterior Corneal Curvature Radii Ratio to Improve the Accuracy of Intraocular Lens Power Calculation: Eom's Adjustment Method

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Mingue Kim; Youngsub Eom; Hwa Lee; Young-Woo Suh; Jong Suk Song; Hyo Myung Kim
TAGS: cornea, intraocular lens implant device
Invest. Ophthalmol. Vis. Sci.. 2018; 59(2):1016-1024. doi: 10.1167/iovs.17-22405

Includes: Supplemental Content

Retina February 2018

EVEREST Report 5: Clinical Outcomes and Treatment Response of Polypoidal Choroidal Vasculopathy Subtypes in a Multicenter, Randomized Controlled Trial

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Colin S. Tan; Louis W. Lim; Wei Kiong Ngo; Tock Han Lim; for the EVEREST Study Group
TAGS: vascular diseases, polyps, randomized controlled trial, diagnostic imaging, treatment outcome, everest trial, everest trials
Invest. Ophthalmol. Vis. Sci.. 2018; 59(2):889-896. doi: 10.1167/iovs.17-22683

Clinical and Epidemiologic Research January 2018

Association of Low Luminance Questionnaire With Objective Functional Measures in Early and Intermediate Age-Related Macular Degeneration

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Atalie C. Thompson; Ulrich F. O. Luhmann; Sandra S. Stinnett; Lejla Vajzovic; Anupama Horne; Cynthia A. Toth; Scott W. Cousins; Eleonora M. Lad
TAGS: psychophysics, questionnaires, vision, eye, age-related macular degeneration, luminance, functional measures
Invest. Ophthalmol. Vis. Sci.. 2018; 59(1):289-297. doi: 10.1167/iovs.17-22528

Clinical and Epidemiologic Research January 2018

Severe Loss of Tritan Color Discrimination in RPE65 Associated Leber Congenital Amaurosis

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Neruban Kumaran; Caterina Ripamonti; Angelos Kalitzeos; Gary S. Rubin; James W. B. Bainbridge; Michel Michaelides
TAGS: color, leber's amaurosis, color vision
Invest. Ophthalmol. Vis. Sci.. 2018; 59(1):85-93. doi: 10.1167/iovs.17-22905

Clinical and Epidemiologic Research January 2018

Risk of Retinal Vein Occlusion in Patients With End-Stage Renal Disease: A 12-Year, Retrospective, Nationwide Cohort Study in South Korea

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Kyung Sik Lee; Ki Heon Nam; Dong Wook Kim; Eui Chun Kang; Hyoung Jun Koh
TAGS: kidney failure, chronic, cohort studies, retinal vein occlusion, retrospective studies, south korea
Invest. Ophthalmol. Vis. Sci.. 2018; 59(1):39-44. doi: 10.1167/iovs.17-22638

Clinical and Epidemiologic Research December 2017

Systemic Inflammation-Associated Proteins and Retinopathy of Prematurity in Infants Born Before the 28th Week of Gestation

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Mari Holm; Tora S. Morken; Raina N. Fichorova; Deborah K. VanderVeen; Elizabeth N. Allred; Olaf Dammann; Alan Leviton; for the ELGAN Study Neonatology and Ophthalmology Committees
TAGS: pregnancy, inflammation, biological markers, infant, retinopathy of prematurity, proteins
Invest. Ophthalmol. Vis. Sci.. 2017; 58(14):6419-6428. doi: 10.1167/iovs.17-21931

Includes: Supplemental Content

Clinical and Epidemiologic Research December 2017

Development and Validation of a Risk Score for Age-Related Macular Degeneration: The STARS Questionnaire

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Cécile Delcourt; Eric Souied; Alice Sanchez; Francesco Bandello; for the STARS Survey Group
TAGS: questionnaires, risk assessment, risk factors, age-related macular degeneration, italian
Invest. Ophthalmol. Vis. Sci.. 2017; 58(14):6399-6407. doi: 10.1167/iovs.17-21819

Clinical and Epidemiologic Research December 2017

Effects of Prenatal Alcohol Exposure on the Visual System of Monkeys Measured at Different Stages of Development

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Vanessa Harrar; Laurent Elkrief; Joseph Bouskila; Ryan Kucera; Anders Fink-Jensen; Jean-François Bouchard; Roberta Palmour; Maurice Ptito
TAGS: ethanol, cercopithecidae, electroretinography, retina, developmental stages, visual system, prenatal alcohol exposure
Invest. Ophthalmol. Vis. Sci.. 2017; 58(14):6282-6291. doi: 10.1167/iovs.17-22181

Includes: Supplemental Content

Clinical and Epidemiologic Research December 2017

Skin Intrinsic Fluorescence and Age-Related Macular Degeneration: The Beaver Dam Eye Study

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Ronald Klein; Kristine E. Lee; John D. Maynard; Stacy M. Meuer; Ronald E. Gangnon; Barbara E. K. Klein
TAGS: cardiovascular diseases, fluorescence, eye, age-related macular degeneration, skin, serum immunosuppressive factor, human
Invest. Ophthalmol. Vis. Sci.. 2017; 58(14):6328-6333. doi: 10.1167/iovs.17-22382

Includes: Supplemental Content

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Family-Based Genome-Wide Association Study of South Indian Pedigrees Supports WNT7B as a Central Corneal Thickness Locus

Clinical Outcomes of Fixed Versus As-Needed Use of Artificial Tears in Dry Eye Disease: A 6-Week, Observer-Masked Phase 4 Clinical Trial

Direct and Indirect Associations Between Diabetes and Intraocular Pressure: The Singapore Epidemiology of Eye Diseases Study

Long Anterior Lens Zonules and Intraocular Pressure

The Economic Burden of Visual Impairment and Comorbid Fatigue: A Cost-of-Illness Study (From a Societal Perspective)

Consistency of Structure-Function Correlation Between Spatially Scaled Visual Field Stimuli and In Vivo OCT Ganglion Cell Counts

Plasma Concentrations of Lutein and Zeaxanthin, Macular Pigment Optical Density, and Their Associations With Cognitive Performances Among Older Adults

Towards Standardization of Quantitative Retinal Vascular Parameters: Comparison of SIVA and VAMPIRE Measurements in the Lothian Birth Cohort 1936

Distribution Pattern of Choroidal Thickness at the Posterior Pole in Chinese Children With Myopia

How Many Subjects are Needed for a Visual Field Normative Database? A Comparison of Ground Truth and Bootstrapped Statistics

Clinical Age-Specific Seasonal Conjunctivitis Patterns and Their Online Detection in Twitter, Blog, Forum, and Comment Social Media Posts

Use of the Posterior/Anterior Corneal Curvature Radii Ratio to Improve the Accuracy of Intraocular Lens Power Calculation: Eom's Adjustment Method

EVEREST Report 5: Clinical Outcomes and Treatment Response of Polypoidal Choroidal Vasculopathy Subtypes in a Multicenter, Randomized Controlled Trial

Association of Low Luminance Questionnaire With Objective Functional Measures in Early and Intermediate Age-Related Macular Degeneration

Severe Loss of Tritan Color Discrimination in RPE65 Associated Leber Congenital Amaurosis

Risk of Retinal Vein Occlusion in Patients With End-Stage Renal Disease: A 12-Year, Retrospective, Nationwide Cohort Study in South Korea

Systemic Inflammation-Associated Proteins and Retinopathy of Prematurity in Infants Born Before the 28th Week of Gestation

Development and Validation of a Risk Score for Age-Related Macular Degeneration: The STARS Questionnaire

Effects of Prenatal Alcohol Exposure on the Visual System of Monkeys Measured at Different Stages of Development

Skin Intrinsic Fluorescence and Age-Related Macular Degeneration: The Beaver Dam Eye Study

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