Clinical and Epidemiologic Research

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Clinical and Epidemiologic Research June 2017

Optic Nerve Tilt, Crescent, Ovality, and Torsion in a Multi-Ethnic Cohort of Young Adults With and Without Myopia

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Wendy L. Marsh-Tootle; Elise Harb; Wei Hou; Qinghua Zhang; Heather A. Anderson; Katherine Weise; Thomas T. Norton; Jane Gwiazda; Leslie Hyman; for the Correction of Myopia Evaluation Trial (COMET) Study Group
TAGS: cohort studies, myopia, optic disk, musculoskeletal torsion, function, eye, optic nerve, young adult, torsion
Invest. Ophthalmol. Vis. Sci.. 2017; 58(7):3158-3171. doi: 10.1167/iovs.16-20860

Includes: Supplemental Content

Anatomy and Pathology/Oncology June 2017

Pattern Recognition Analysis of Age-Related Retinal Ganglion Cell Signatures in the Human Eye

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Nayuta Yoshioka; Barbara Zangerl; Lisa Nivison-Smith; Sieu K. Khuu; Bryan W. Jones; Rebecca L. Pfeiffer; Robert E. Marc; Michael Kalloniatis
TAGS: cohort studies, pattern recognition, regression analysis, retinal ganglion cells, eye, linear regression
Invest. Ophthalmol. Vis. Sci.. 2017; 58(7):3086-3099. doi: 10.1167/iovs.17-21450

Includes: Supplemental Content

Clinical and Epidemiologic Research June 2017

Visual Sensory and Visual-Cognitive Function and Rate of Crash and Near-Crash Involvement Among Older Drivers Using Naturalistic Driving Data

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Carrie Huisingh; Emily B. Levitan; Marguerite R. Irvin; Paul MacLennan; Virginia Wadley; Cynthia Owsley
TAGS: vision, older drivers
Invest. Ophthalmol. Vis. Sci.. 2017; 58(7):2959-2967. doi: 10.1167/iovs.17-21482

Clinical and Epidemiologic Research June 2017

Effect of Mandarin Orange Yogurt on Allergic Conjunctivitis Induced by Conjunctival Allergen Challenge

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Yuko Hara; Atsushi Shiraishi; Yuri Sakane; Yuki Takezawa; Tomoyuki Kamao; Yuichi Ohashi; Sho Yasunaga; Takuya Sugahara
TAGS: conjunctivitis, allergens, allergic conjunctivitis, yogurt, body temperature, conjunctiva, temperature, mandarin
Invest. Ophthalmol. Vis. Sci.. 2017; 58(7):2922-2929. doi: 10.1167/iovs.16-21206

Clinical and Epidemiologic Research May 2017

Nighttime Driving in Older Adults: Effects of Glare and Association With Mesopic Visual Function

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Janessa A. Kimlin; Alex A. Black; Joanne M. Wood
TAGS: glare, vision, elderly
Invest. Ophthalmol. Vis. Sci.. 2017; 58(5):2796-2803. doi: 10.1167/iovs.16-21219

Clinical and Epidemiologic Research May 2017

The Impact of Lens Opacity on SD-OCT Retinal Nerve Fiber Layer and Bruch's Membrane Opening Measurements Using the Anatomical Positioning System (APS)

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Matthias M. Mauschitz; Felix Roth; Frank G. Holz; Monique M. B. Breteler; Robert P. Finger
TAGS: bruch's basal membrane, cataract, cataract surgery, retinal nerve fiber layer, spectral-domain optical coherence tomography
Invest. Ophthalmol. Vis. Sci.. 2017; 58(5):2804-2809. doi: 10.1167/iovs.17-21675

Editorial May 2017

Foreword: Biomarkers and Surrogate Endpoints in Ophthalmic Clinical Research

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Edoardo Villani; Stela Vujosevic
TAGS: biological markers, eye, surrogate endpoints, clinical research
Invest. Ophthalmol. Vis. Sci.. 2017; 58(6):BIOi-BIOii. doi: 10.1167/iovs.17-22128

Clinical and Epidemiologic Research May 2017

Radiologic Parameters of Orbital Bone Remodeling in Thyroid Eye Disease

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Nicholas Y. Q. Tan; Yuan-Yuh Leong; Stephanie S. Lang; Zin M. Htoon; Stephanie M. Young; Gangadhara Sundar
TAGS: computed tomography, graves' ophthalmopathy, muscle of orbit, orbit, radiology specialty, zygomatic bone, medial rectus muscle, volume
Invest. Ophthalmol. Vis. Sci.. 2017; 58(5):2527-2533. doi: 10.1167/iovs.16-21035

Clinical and Epidemiologic Research May 2017

Urinary Isoprostane Levels and Age-Related Macular Degeneration

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Charumathi Sabanayagam; Weng Kit Lye; Andrzej Januszewski; Riswana Banu Binte Mohammed Abdul; Gemmy Chui Ming Cheung; Neelam Kumari; Tien Y. Wong; Ching-Yu Cheng; Ecosse Lamoureux
TAGS: oxidative stress, body mass index procedure, isoprostanes, urinary tract, age-related macular degeneration
Invest. Ophthalmol. Vis. Sci.. 2017; 58(5):2538-2543. doi: 10.1167/iovs.16-21263

Special Issue May 2017

The Growing Need for Validated Biomarkers and Endpoints for Dry Eye Clinical Research

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Neeta S. Roy; Yi Wei; Eric Kuklinski; Penny A. Asbell
TAGS: biological markers, dry eye syndromes, surrogate endpoints, clinical research
Invest. Ophthalmol. Vis. Sci.. 2017; 58(6):BIO1-BIO19. doi: 10.1167/iovs.17-21709

Clinical and Epidemiologic Research May 2017

Progressive Retinal Vasodilation in Patients With Type 1 Diabetes: A Longitudinal Study of Retinal Vascular Geometry

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Gerald Liew; Paul Benitez-Aguirre; Maria E. Craig; Alicia J. Jenkins; Lauren A. B. Hodgson; Annette Kifley; Paul Mitchell; Tien Y. Wong; Kim Donaghue
TAGS: diabetes mellitus, type 1, diabetic retinopathy, hemoglobin a, glycosylated, longitudinal studies, retinal diseases, vasodilation, diameter
Invest. Ophthalmol. Vis. Sci.. 2017; 58(5):2503-2509. doi: 10.1167/iovs.16-21015

Includes: Supplemental Content

Clinical and Epidemiologic Research May 2017

Dynamic Responses in Retinal Vessel Caliber With Flicker Light Stimulation and Risk of Diabetic Retinopathy and Its Progression

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Laurence S. Lim; Lieng H. Ling; Peng Guan Ong; Wallace Foulds; E. Shyong Tai; Tien Yin Wong
TAGS: diabetes mellitus, diabetic retinopathy, retinal vessels, photopsia, retinal vascular caliber
Invest. Ophthalmol. Vis. Sci.. 2017; 58(5):2449-2455. doi: 10.1167/iovs.16-21008

Clinical and Epidemiologic Research April 2017

Visual Impairment, Undercorrected Refractive Errors, and Activity Limitations in Older Adults: Findings From the Three-City Alienor Study

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Virginie Naël; Karine Pérès; Isabelle Carrière; Vincent Daien; Anne-Catherine Scherlen; Angelo Arleo; Jean-Francois Korobelnik; Cécile Delcourt; Catherine Helmer
TAGS: activities of daily living, refractive errors, visual impairment, visual acuity, elderly, mobility, social participation, instrumental activities of daily living
Invest. Ophthalmol. Vis. Sci.. 2017; 58(4):2359-2365. doi: 10.1167/iovs.17-21525

Clinical and Epidemiologic Research April 2017

Vitreomacular Adhesion and Its Association With Age-Related Macular Degeneration in a Population-Based Setting: The Alienor Study

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Sarra Gattoussi; Audrey Cougnard-Grégoire; Marie-Noëlle Delyfer; Marie-Bénédicte Rougier; Cédric Schweitzer; Cécile Delcourt; Jean-François Korobelnik
TAGS: cataract surgery, risk factors, age-related macular degeneration, vitreomacular adhesions, spectral-domain optical coherence tomography
Invest. Ophthalmol. Vis. Sci.. 2017; 58(4):2180-2186. doi: 10.1167/iovs.16-20741

Clinical and Epidemiologic Research March 2017

Sex Disparity in Survival of Patients With Uveal Melanoma: Better Survival Rates in Women Than in Men in South Korea

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San Jun Park; Chang-Mo Oh; Bora Yeon; Hyunsoon Cho; Kyu Hyung Park
TAGS: survival rate, intraocular melanoma, gender disparities, south korea
Invest. Ophthalmol. Vis. Sci.. 2017; 58(3):1909-1915. doi: 10.1167/iovs.16-20077

Includes: Supplemental Content

Clinical and Epidemiologic Research March 2017

A New Method of Magnification Correction for Accurately Measuring Retinal Vessel Calibers From Fundus Photographs

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Aiko Iwase; Akihiko Sekine; Jun Suehiro; Kenji Tanaka; Yumiko Kawasaki; Ryo Kawasaki; Michael J. Sinai; Makoto Araie
TAGS: eye, fundus photography, retinal vascular caliber, magnification
Invest. Ophthalmol. Vis. Sci.. 2017; 58(3):1858-1864. doi: 10.1167/iovs.16-21202

Clinical and Epidemiologic Research March 2017

The Response AC/A Ratio Before and After the Onset of Myopia

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Donald O. Mutti; G. Lynn Mitchell; Lisa A. Jones-Jordan; Susan A. Cotter; Robert N. Kleinstein; Ruth E. Manny; J. Daniel Twelker; Karla Zadnik; for the CLEERE Study Group
TAGS: child, myopia, refractive errors
Invest. Ophthalmol. Vis. Sci.. 2017; 58(3):1594-1602. doi: 10.1167/iovs.16-19093

Genetics March 2017

Systematic Functional Testing of Rare Variants: Contributions of CFI to Age-Related Macular Degeneration

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Perciliz L. Tan; Melanie E. Garrett; Jason R. Willer; Peter A. Campochiaro; Betsy Campochiaro; Donald J. Zack; Allison E. Ashley-Koch; Nicholas Katsanis
TAGS: alleles, cohort studies, age-related macular degeneration, cultural formulation interview
Invest. Ophthalmol. Vis. Sci.. 2017; 58(3):1570-1576. doi: 10.1167/iovs.16-20867

Includes: Supplemental Content

Articles March 2017

Validation of the Total Visual Acuity Extraction Algorithm (TOVA) for Automated Extraction of Visual Acuity Data From Free Text, Unstructured Clinical Records

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Douglas M. Baughman; Grace L. Su; Irena Tsui; Cecilia S. Lee; Aaron Y. Lee
TAGS: visual acuity, eye, handedness, electronic medical records, visual analogue pain scale
Trans. Vis. Sci. Tech.. 2017; 6(2):2. doi: 10.1167/tvst.6.2.2

Clinical and Epidemiologic Research February 2017

Time Outdoors at Specific Ages During Early Childhood and the Risk of Incident Myopia

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Rupal L. Shah; Yu Huang; Jeremy A. Guggenheim; Cathy Williams
TAGS: child, myopia
Invest. Ophthalmol. Vis. Sci.. 2017; 58(2):1158-1166. doi: 10.1167/iovs.16-20894

Includes: Supplemental Content

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Optic Nerve Tilt, Crescent, Ovality, and Torsion in a Multi-Ethnic Cohort of Young Adults With and Without Myopia

Pattern Recognition Analysis of Age-Related Retinal Ganglion Cell Signatures in the Human Eye

Visual Sensory and Visual-Cognitive Function and Rate of Crash and Near-Crash Involvement Among Older Drivers Using Naturalistic Driving Data

Effect of Mandarin Orange Yogurt on Allergic Conjunctivitis Induced by Conjunctival Allergen Challenge

Nighttime Driving in Older Adults: Effects of Glare and Association With Mesopic Visual Function

The Impact of Lens Opacity on SD-OCT Retinal Nerve Fiber Layer and Bruch's Membrane Opening Measurements Using the Anatomical Positioning System (APS)

Foreword: Biomarkers and Surrogate Endpoints in Ophthalmic Clinical Research

Radiologic Parameters of Orbital Bone Remodeling in Thyroid Eye Disease

Urinary Isoprostane Levels and Age-Related Macular Degeneration

The Growing Need for Validated Biomarkers and Endpoints for Dry Eye Clinical Research

Progressive Retinal Vasodilation in Patients With Type 1 Diabetes: A Longitudinal Study of Retinal Vascular Geometry

Dynamic Responses in Retinal Vessel Caliber With Flicker Light Stimulation and Risk of Diabetic Retinopathy and Its Progression

Visual Impairment, Undercorrected Refractive Errors, and Activity Limitations in Older Adults: Findings From the Three-City Alienor Study

Vitreomacular Adhesion and Its Association With Age-Related Macular Degeneration in a Population-Based Setting: The Alienor Study

Sex Disparity in Survival of Patients With Uveal Melanoma: Better Survival Rates in Women Than in Men in South Korea

A New Method of Magnification Correction for Accurately Measuring Retinal Vessel Calibers From Fundus Photographs

The Response AC/A Ratio Before and After the Onset of Myopia

Systematic Functional Testing of Rare Variants: Contributions of CFI to Age-Related Macular Degeneration

Validation of the Total Visual Acuity Extraction Algorithm (TOVA) for Automated Extraction of Visual Acuity Data From Free Text, Unstructured Clinical Records

Time Outdoors at Specific Ages During Early Childhood and the Risk of Incident Myopia

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