Clinical and Epidemiologic Research

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Clinical and Epidemiologic Research August 2017

Subclinical Decrease in Central Inner Retinal Activity Is Associated With Myopia Development in Children

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Serena Zhe-Chuang Li; Wing-Yan Yu; Kai-Yip Choi; Christie Hang-I Lam; Yamunadevi Lakshmanan; Francisca Siu-Yin Wong; Henry Ho-Lung Chan
TAGS: child, child development, myopia, refractive errors
Invest. Ophthalmol. Vis. Sci.. 2017; 58(10):4019-4026. doi: 10.1167/iovs.16-21279

Special Issue August 2017

Diabetic Retinopathy Phenotypes of Progression to Macular Edema: Pooled Analysis From Independent Longitudinal Studies of up to 2 Years' Duration

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José Cunha-Vaz; Luísa Ribeiro; Miguel Costa; Rafael Simó
TAGS: phenotype, diabetic retinopathy, longitudinal studies, nonproliferative diabetic retinopathy, macular edema
Invest. Ophthalmol. Vis. Sci.. 2017; 58(6):BIO206-BIO210. doi: 10.1167/iovs.17-21780

Clinical and Epidemiologic Research August 2017

Uvemaster: A Mobile App-Based Decision Support System for the Differential Diagnosis of Uveitis

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Jose A. Gegundez-Fernandez; Jose I. Fernandez-Vigo; David Diaz-Valle; Rosalia Mendez-Fernandez; Ricardo Cuiña-Sardiña; Enrique Santos-Bueso; Jose M. Benitez-del-Castillo
TAGS: decision support systems, diagnosis, differential, syndrome, uveitis
Invest. Ophthalmol. Vis. Sci.. 2017; 58(10):3931-3939. doi: 10.1167/iovs.17-21493

Includes: Supplemental Content

Clinical and Epidemiologic Research July 2017

Correlations Between Macular, Skin, and Serum Carotenoids

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Christopher D. Conrady; James P. Bell; Brian M. Besch; Aruna Gorusupudi; Kelliann Farnsworth; Igor Ermakov; Mohsen Sharifzadeh; Maia Ermakova; Werner Gellermann; Paul S. Bernstein
TAGS: carotenoids, skin, macular pigment
Invest. Ophthalmol. Vis. Sci.. 2017; 58(9):3616-3627. doi: 10.1167/iovs.17-21818

Clinical and Epidemiologic Research July 2017

Optical Coherence Tomography Angiography of the Superficial Microvasculature in the Macular and Peripapillary Areas in Glaucomatous and Healthy Eyes

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Henry Shen-Lih Chen; Chun-Hsiu Liu; Wei-Chi Wu; Hsiao-Jung Tseng; Yung-Sung Lee
TAGS: angiogram, glaucoma, open-angle glaucoma, eye, optical coherence tomography, microvascular network
Invest. Ophthalmol. Vis. Sci.. 2017; 58(9):3637-3645. doi: 10.1167/iovs.17-21846

Clinical and Epidemiologic Research July 2017

A Global View on Output and Outcomes of Cataract Surgery With National Indices of Socioeconomic Development

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Wei Wang; William Yan; Andreas Müller; Mingguang He
TAGS: blindness, cataract, cataract surgery, socioeconomic factors, surgical procedures, operative
Invest. Ophthalmol. Vis. Sci.. 2017; 58(9):3669-3676. doi: 10.1167/iovs.17-21489

Special Issue July 2017

Detection of Functional Change Using Cluster Trend Analysis in Glaucoma

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Stuart K. Gardiner; Steven L. Mansberger; Shaban Demirel
TAGS: glaucoma, cohort studies, perimetry, visual fields, eye, specificity of diagnostic test, trend
Invest. Ophthalmol. Vis. Sci.. 2017; 58(6):BIO180-BIO190. doi: 10.1167/iovs.17-21562

Clinical and Epidemiologic Research July 2017

Optical Coherence Tomography Features Preceding the Onset of Advanced Age-Related Macular Degeneration

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Daniela Ferrara; Rachel E. Silver; Ricardo N. Louzada; Eduardo A. Novais; Giliann K. Collins; Johanna M. Seddon
TAGS: eye, age-related macular degeneration, optical coherence tomography
Invest. Ophthalmol. Vis. Sci.. 2017; 58(9):3519-3529. doi: 10.1167/iovs.17-21696

Includes: Supplemental Content

Clinical and Epidemiologic Research July 2017

Association Between Visual Function Response and Reduction of Inflammation in Noninfectious Uveitis of the Posterior Segment

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Benedicte Lescrauwaet; Elisabetta Miserocchi; Stephan Thurau; Bahram Bodaghi; Luc Duchateau; Thomas Verstraeten; Sunil Srivastava
TAGS: inflammation, uveitis, vision
Invest. Ophthalmol. Vis. Sci.. 2017; 58(9):3555-3562. doi: 10.1167/iovs.17-22049

Includes: Supplemental Content

Clinical and Epidemiologic Research July 2017

Peripheral Design of Progressive Addition Lenses and the Lag of Accommodation in Myopes

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Tim Schilling; Arne Ohlendorf; Saulius R. Varnas; Siegfried Wahl
TAGS: visual accommodation, lens, crystalline, lens (device), papillon-lefevre disease, vision, advanced life support, pediatric, periarterial lymphatic sheath
Invest. Ophthalmol. Vis. Sci.. 2017; 58(9):3319-3324. doi: 10.1167/iovs.17-21589

Clinical and Epidemiologic Research June 2017

The Magnitude of Hypotony and Time Course of Intraocular Pressure Recovery Following Anterior Chamber Cannulation in Nonhuman Primates

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Jessica V. Jasien; Carrie Huisingh; Christopher A. Girkin; J. Crawford Downs
TAGS: anterior chamber of eye, catheterization, needle device, primates, recovery of function, time factors, intraocular pressure
Invest. Ophthalmol. Vis. Sci.. 2017; 58(7):3225-3230. doi: 10.1167/iovs.17-21833

Clinical and Epidemiologic Research June 2017

Trachomatous Scarring and Infection With Non– Chlamydia Trachomatis Bacteria in Women in Kongwa, Tanzania

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Jacob T. Cox; Mabula J. Kasubi; Beatriz E. Muñoz; Andrea I. Zambrano; Gregory S. Greene; Harran Mkocha; Meraf A. Wolle; Sheila K. West
TAGS: chlamydia trachomatis, cicatrix, tanzania, trachoma, infection, bacteria, conjunctiva
Invest. Ophthalmol. Vis. Sci.. 2017; 58(7):3249-3253. doi: 10.1167/iovs.17-21519

Clinical and Epidemiologic Research June 2017

The Impact of Lens Opacity on SD-OCT Retinal Nerve Fiber Layer and Bruch's Membrane Opening Measurements Using the Anatomical Positioning System (APS)

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Matthias M. Mauschitz; Felix Roth; Frank G. Holz; Monique M. B. Breteler; Robert P. Finger
TAGS: bruch's basal membrane, cataract, cataract surgery, retinal nerve fiber layer, spectral-domain optical coherence tomography
Invest. Ophthalmol. Vis. Sci.. 2017; 58(5):2804-2809. doi: 10.1167/iovs.17-21675

Clinical and Epidemiologic Research June 2017

Optic Nerve Tilt, Crescent, Ovality, and Torsion in a Multi-Ethnic Cohort of Young Adults With and Without Myopia

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Wendy L. Marsh-Tootle; Elise Harb; Wei Hou; Qinghua Zhang; Heather A. Anderson; Katherine Weise; Thomas T. Norton; Jane Gwiazda; Leslie Hyman; for the Correction of Myopia Evaluation Trial (COMET) Study Group
TAGS: cohort studies, myopia, optic disk, musculoskeletal torsion, function, eye, optic nerve, young adult, torsion
Invest. Ophthalmol. Vis. Sci.. 2017; 58(7):3158-3171. doi: 10.1167/iovs.16-20860

Includes: Supplemental Content

Anatomy and Pathology/Oncology June 2017

Pattern Recognition Analysis of Age-Related Retinal Ganglion Cell Signatures in the Human Eye

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Nayuta Yoshioka; Barbara Zangerl; Lisa Nivison-Smith; Sieu K. Khuu; Bryan W. Jones; Rebecca L. Pfeiffer; Robert E. Marc; Michael Kalloniatis
TAGS: cohort studies, pattern recognition, regression analysis, retinal ganglion cells, eye, linear regression
Invest. Ophthalmol. Vis. Sci.. 2017; 58(7):3086-3099. doi: 10.1167/iovs.17-21450

Includes: Supplemental Content

Clinical and Epidemiologic Research June 2017

Visual Sensory and Visual-Cognitive Function and Rate of Crash and Near-Crash Involvement Among Older Drivers Using Naturalistic Driving Data

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Carrie Huisingh; Emily B. Levitan; Marguerite R. Irvin; Paul MacLennan; Virginia Wadley; Cynthia Owsley
TAGS: vision, older drivers
Invest. Ophthalmol. Vis. Sci.. 2017; 58(7):2959-2967. doi: 10.1167/iovs.17-21482

Clinical and Epidemiologic Research June 2017

Effect of Mandarin Orange Yogurt on Allergic Conjunctivitis Induced by Conjunctival Allergen Challenge

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Yuko Hara; Atsushi Shiraishi; Yuri Sakane; Yuki Takezawa; Tomoyuki Kamao; Yuichi Ohashi; Sho Yasunaga; Takuya Sugahara
TAGS: conjunctivitis, allergens, allergic conjunctivitis, yogurt, body temperature, conjunctiva, temperature, mandarin
Invest. Ophthalmol. Vis. Sci.. 2017; 58(7):2922-2929. doi: 10.1167/iovs.16-21206

Clinical and Epidemiologic Research May 2017

Nighttime Driving in Older Adults: Effects of Glare and Association With Mesopic Visual Function

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Janessa A. Kimlin; Alex A. Black; Joanne M. Wood
TAGS: glare, vision, elderly
Invest. Ophthalmol. Vis. Sci.. 2017; 58(5):2796-2803. doi: 10.1167/iovs.16-21219

Editorial May 2017

Foreword: Biomarkers and Surrogate Endpoints in Ophthalmic Clinical Research

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Edoardo Villani; Stela Vujosevic
TAGS: biological markers, eye, surrogate endpoints, clinical research
Invest. Ophthalmol. Vis. Sci.. 2017; 58(6):BIOi-BIOii. doi: 10.1167/iovs.17-22128

Clinical and Epidemiologic Research May 2017

Radiologic Parameters of Orbital Bone Remodeling in Thyroid Eye Disease

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Nicholas Y. Q. Tan; Yuan-Yuh Leong; Stephanie S. Lang; Zin M. Htoon; Stephanie M. Young; Gangadhara Sundar
TAGS: computed tomography, graves' ophthalmopathy, muscle of orbit, orbit, radiology specialty, zygomatic bone, medial rectus muscle, volume
Invest. Ophthalmol. Vis. Sci.. 2017; 58(5):2527-2533. doi: 10.1167/iovs.16-21035

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Subclinical Decrease in Central Inner Retinal Activity Is Associated With Myopia Development in Children

Diabetic Retinopathy Phenotypes of Progression to Macular Edema: Pooled Analysis From Independent Longitudinal Studies of up to 2 Years' Duration

Uvemaster: A Mobile App-Based Decision Support System for the Differential Diagnosis of Uveitis

Correlations Between Macular, Skin, and Serum Carotenoids

Optical Coherence Tomography Angiography of the Superficial Microvasculature in the Macular and Peripapillary Areas in Glaucomatous and Healthy Eyes

A Global View on Output and Outcomes of Cataract Surgery With National Indices of Socioeconomic Development

Detection of Functional Change Using Cluster Trend Analysis in Glaucoma

Optical Coherence Tomography Features Preceding the Onset of Advanced Age-Related Macular Degeneration

Association Between Visual Function Response and Reduction of Inflammation in Noninfectious Uveitis of the Posterior Segment

Peripheral Design of Progressive Addition Lenses and the Lag of Accommodation in Myopes

The Magnitude of Hypotony and Time Course of Intraocular Pressure Recovery Following Anterior Chamber Cannulation in Nonhuman Primates

Trachomatous Scarring and Infection With Non– Chlamydia Trachomatis Bacteria in Women in Kongwa, Tanzania

The Impact of Lens Opacity on SD-OCT Retinal Nerve Fiber Layer and Bruch's Membrane Opening Measurements Using the Anatomical Positioning System (APS)

Optic Nerve Tilt, Crescent, Ovality, and Torsion in a Multi-Ethnic Cohort of Young Adults With and Without Myopia

Pattern Recognition Analysis of Age-Related Retinal Ganglion Cell Signatures in the Human Eye

Visual Sensory and Visual-Cognitive Function and Rate of Crash and Near-Crash Involvement Among Older Drivers Using Naturalistic Driving Data

Effect of Mandarin Orange Yogurt on Allergic Conjunctivitis Induced by Conjunctival Allergen Challenge

Nighttime Driving in Older Adults: Effects of Glare and Association With Mesopic Visual Function

Foreword: Biomarkers and Surrogate Endpoints in Ophthalmic Clinical Research

Radiologic Parameters of Orbital Bone Remodeling in Thyroid Eye Disease

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