Cornea

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Articles June 2022

Healing Ability of Central Corneal Epithelium in Rabbit Ocular Surface Injury Models

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Wang Zhang; Xihong Lan; Jin Zhu; Canwei Zhang; Ying Huang; Kunlun Mo; Jieying Tan; Huizhen Guo; Huaxing Huang; Mingsen Li; Hong Ouyang; Li Wang
TAGS: chronic exertional compartment syndrome, corneal epithelium, ocular surfaces, oryctolagus cuniculus, wound healing, wounds and injuries, genes, cornea
Trans. Vis. Sci. Tech.. 2022; 11(6):28. doi: https://doi.org/10.1167/tvst.11.6.28

Includes: Supplemental Content

Articles June 2022

Development of an In Situ Printing System With Human Platelet Lysate-Based Bio-Adhesive to Treat Corneal Perforations

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Jingjing You; Hannah Frazer; Sepidar Sayyar; Zhi Chen; Xiao Liu; Adam Taylor; Benjamin Filippi; Stephen Beirne; Innes Wise; Constantinos Petsoglou; Chris Hodge; Gordon Wallace; Gerard Sutton
TAGS: adhesives, perforation of cornea, printing, lysate, cornea, blood platelets
Trans. Vis. Sci. Tech.. 2022; 11(6):26. doi: https://doi.org/10.1167/tvst.11.6.26

Includes: Multimedia, Supplemental Content

Articles June 2022

Segmentation and Evaluation of Corneal Nerves and Dendritic Cells From In Vivo Confocal Microscopy Images Using Deep Learning

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Md Asif Khan Setu; Stefan Schmidt; Gwen Musial; Michael E. Stern; Philipp Steven
TAGS: cornea, datasets, deep learning, dendritic cells, finnish congenital nephrotic syndrome, microscopy, confocal, neurons, nerve fibers, craniofrontonasal dysplasia
Trans. Vis. Sci. Tech.. 2022; 11(6):24. doi: https://doi.org/10.1167/tvst.11.6.24

Includes: Supplemental Content

Articles June 2022

Corneal Lenticule Creation Using a New Solid-State Femtosecond Laser Measured by Spectral Domain OCT in a Porcine Eye Model

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Christoph Lwowski; Anna Voigt; Karel Van Keer; Thomas Kohnen
TAGS: cornea, eye, femtosecond pulsed lasers, solids, spectral domain-optical coherence tomography, suidae, lasers
Trans. Vis. Sci. Tech.. 2022; 11(6):20. doi: https://doi.org/10.1167/tvst.11.6.20

Biochemistry and Molecular Biology June 2022

Early Dry Eye Disease Onset in a NOD.H-2 h4 Mouse Model of Sjögren's Syndrome

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Lili Li; Kimberly J. Jasmer; Jean M. Camden; Lucas T. Woods; Adam L. Martin; Yong Yang; Maria Layton; Michael J. Petris; Olga J. Baker; Gary A. Weisman; Carisa K. Petris
TAGS: mice, dry eye syndromes, sjogren's syndrome
Invest. Ophthalmol. Vis. Sci.. 2022; 63(6):18. doi: https://doi.org/10.1167/iovs.63.6.18

Includes: Supplemental Content

Cornea June 2022

Lysozyme Protects Against Severe Acute Respiratory Syndrome Coronavirus 2 Infection and Inflammation in Human Corneal Epithelial Cells

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Yinting Song; Haokun Zhang; Yanfang Zhu; Xiao Zhao; Yi Lei; Wei Zhou; Jinguo Yu; Xue Dong; Xiaohong Wang; Mei Du; Hua Yan
TAGS: covid-19, infections, inflammation, muramidase, proteins, severe acute respiratory syndrome, corneal epithelial cells, sars-cov-2, coronavirus
Invest. Ophthalmol. Vis. Sci.. 2022; 63(6):16. doi: https://doi.org/10.1167/iovs.63.6.16

Articles June 2022

Quantitative Assessment of Biomechanical Properties of the Human Keratoconus Cornea Using Acoustic Radiation Force Optical Coherence Elastography

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Yanzhi Zhao; Hongwei Yang; Yingjie Li; Yongbo Wang; Xiao Han; Yirui Zhu; Yubao Zhang; Guofu Huang
TAGS: cornea, elasticity imaging techniques, keratoconus, acoustics, optics, radiation, elasticity
Trans. Vis. Sci. Tech.. 2022; 11(6):4. doi: https://doi.org/10.1167/tvst.11.6.4

Cornea June 2022

Corneal Epithelium–Derived Netrin-1 Alleviates Dry Eye Disease via Regulating Dendritic Cell Activation

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Chaoqun Yu; Peng Chen; Jing Xu; Susu Wei; Qilong Cao; Chuanlong Guo; Xianggen Wu; Guohu Di
TAGS: cornea, corneal epithelium, dendritic cells, dry eye syndromes, mice, netrin-1, regulation, antibodies
Invest. Ophthalmol. Vis. Sci.. 2022; 63(6):1. doi: https://doi.org/10.1167/iovs.63.6.1

Articles May 2022

Dynamic Contrast Microscopic Optical Coherence Tomography As a Novel Method for Assessing Corneal Epithelium During Exposure to Benzalkonium Chloride

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Gwen Musial; Tabea Kohlfaerber; Martin Ahrens; Hinnerk Schulz-Hildebrandt; Philipp Steven; Gereon Hüttmann
TAGS: benzalkonium chloride, cornea, corneal epithelium, epithelium, eye, optical coherence tomography, diagnostic imaging, cell motility
Trans. Vis. Sci. Tech.. 2022; 11(5):28. doi: https://doi.org/10.1167/tvst.11.5.28

Includes: Supplemental Content

Anatomy and Pathology/Oncology May 2022

Scleral Cross-Linking in Form-Deprivation Myopic Guinea Pig Eyes Leads to Glaucomatous Changes

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Lei Guo; Rui Hua; Xinxin Zhang; Ting Yu Yan; Yang Tong; Xin Zhao; Shi Chao Chen; Moying Wang; Neil M. Bressler; Jun Kong
TAGS: corneal collagen cross-linking, cross-linking, eye, glaucoma, guinea, sclera, myopia
Invest. Ophthalmol. Vis. Sci.. 2022; 63(5):24. doi: https://doi.org/10.1167/iovs.63.5.24

Cornea May 2022

Comprehensive Analysis Identified the Circadian Clock and Global Circadian Gene Expression in Human Corneal Endothelial Cells

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Hiroko Nakai; Yoshiki Tsuchiya; Nobuya Koike; Taiki Asano; Morio Ueno; Yasuhiro Umemura; Yuh Sasawaki; Ryutaro Ono; Junji Hamuro; Chie Sotozono; Kazuhiro Yagita
TAGS: circadian clocks, cornea, endothelial cells, gene expression, chronic exertional compartment syndrome, genes, rhythm, bioluminescence
Invest. Ophthalmol. Vis. Sci.. 2022; 63(5):16. doi: https://doi.org/10.1167/iovs.63.5.16

Includes: Multimedia, Supplemental Content

Cornea May 2022

Shotgun Proteomics for the Identification and Profiling of the Tear Proteome of Keratoconus Patients

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Maite López-López; Uxía Regueiro; Susana Belén Bravo; María del Pilar Chantada-Vázquez; Carmen Pena; Elío Díez-Feijoo; Pablo Hervella; Isabel Lema
TAGS: keratoconus, proteins, proteome, proteomics, enzyme-linked immunosorbent assay
Invest. Ophthalmol. Vis. Sci.. 2022; 63(5):12. doi: https://doi.org/10.1167/iovs.63.5.12

Includes: Supplemental Content

Articles May 2022

Posttransplant VEGFR1R2 Trap Eye Drops Inhibit Corneal (Lymph)angiogenesis and Improve Corneal Allograft Survival in Eyes at High Risk of Rejection

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Wei Zhang; Alfrun Schönberg; Felix Bock; Claus Cursiefen
TAGS: cd40 ligand, cornea, eye, eyedrops, keratoplasty, rejection (psychology), telomeric repeat amplification protocol, thyroid hormone associated protein complex, allografting, transplantation
Trans. Vis. Sci. Tech.. 2022; 11(5):6. doi: https://doi.org/10.1167/tvst.11.5.6

Includes: Supplemental Content

Cornea May 2022

Melatonin Attenuates LPS-Induced Proinflammatory Cytokine Response and Lipogenesis in Human Meibomian Gland Epithelial Cells via MAPK/NF-κB Pathway

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Ren Liu; Jing Li; Yue Xu; Ziyan Chen; Huijing Ye; Jinhui Tang; Lai Wei; Lingyi Liang
TAGS: cytokine, epithelial cells, lipogenesis, meibomian gland, melatonin, mitogen-activated protein kinases, proteins, toll-like receptor 4
Invest. Ophthalmol. Vis. Sci.. 2022; 63(5):6. doi: https://doi.org/10.1167/iovs.63.5.6

Includes: Supplemental Content

Articles May 2022

Tear Strip Meniscometry and Its Clinical Application: Analysis of More Than 2000 Cases

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Keiichi Miyasaka; Masahiko Ayaki; Kazuno Negishi
TAGS: cornea, dry eye syndromes, fluorescein stain method, ocular surfaces, pain, schirmer tear test procedure, signs and symptoms, roc curve, joint meniscus, fluorescein
Trans. Vis. Sci. Tech.. 2022; 11(5):3. doi: https://doi.org/10.1167/tvst.11.5.3

Includes: Supplemental Content

Cornea May 2022

Limbal Niche Cells and Three-Dimensional Matrigel-Induced Dedifferentiation of Mature Corneal Epithelial Cells

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Hui Zhu; Wei Wang; Yongyao Tan; Guanyu Su; Lingjuan Xu; Meng lin Jiang; Shen Li; Yaa-Jyuhn James Meir; Yunming Wang; Guigang Li; Huamin Zhou
TAGS: anaplasia, corneal epithelial cells, epithelial cells, epithelium, cornea, stem cells
Invest. Ophthalmol. Vis. Sci.. 2022; 63(5):1. doi: https://doi.org/10.1167/iovs.63.5.1

Includes: Supplemental Content

Cornea April 2022

Repressed miR-34a Expression Dictates the Cell Fate to Corneal Endothelium Failure

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Junji Hamuro; Kazuko Asada; Morio Ueno; Tomoko Yamashita; Atsushi Mukai; Tomoko Fujita; Eiko Ito; Nao Hiramoto; Munetoyo Toda; Chie Sotozono; Shigeru Kinoshita
TAGS: cd44 antigens, cells, corneal endothelium, gelatinase a, homing-associated cell adhesion molecule, micrornas, mitochondria, patient simulation, prostate health index, protected health information
Invest. Ophthalmol. Vis. Sci.. 2022; 63(4):22. doi: https://doi.org/10.1167/iovs.63.4.22

Includes: Supplemental Content

Cornea April 2022

Analysis of MicroRNA Expression in Tears of Patients with Herpes Epithelial Keratitis: A Preliminary Study

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Yu Jeong Kim; Yeji Yeon; Won June Lee; Yong Un Shin; Heeyoon Cho; Han Woong Lim; Min Ho Kang
TAGS: micrornas, epithelial keratitis, simplexvirus, ulcer
Invest. Ophthalmol. Vis. Sci.. 2022; 63(4):21. doi: https://doi.org/10.1167/iovs.63.4.21

Cornea April 2022

Forkhead Domain Inhibitor-6 Suppresses Corneal Neovascularization and Subsequent Fibrosis After Alkali Burn in Rats

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Chunlin Lan; Guo Liu; Longxiang Huang; Xizhen Wang; Junkai Tan; Yun Wang; Ning Fan; Yihua Zhu; Man Yu; Xuyang Liu
TAGS: alkalies, burns, cornea, corneal neovascularization, fibrosis, inflammation, rats
Invest. Ophthalmol. Vis. Sci.. 2022; 63(4):14. doi: https://doi.org/10.1167/iovs.63.4.14

Articles April 2022

Prediction of Subjective Refraction From Anterior Corneal Surface, Eye Lengths, and Age Using Machine Learning Algorithms

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Julián Espinosa; Jorge Pérez; Asier Villanueva
TAGS: cornea, eye, machine learning, refraction, spatial vectors, disease vectors
Trans. Vis. Sci. Tech.. 2022; 11(4):8. doi: https://doi.org/10.1167/tvst.11.4.8

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Healing Ability of Central Corneal Epithelium in Rabbit Ocular Surface Injury Models

Development of an In Situ Printing System With Human Platelet Lysate-Based Bio-Adhesive to Treat Corneal Perforations

Segmentation and Evaluation of Corneal Nerves and Dendritic Cells From In Vivo Confocal Microscopy Images Using Deep Learning

Corneal Lenticule Creation Using a New Solid-State Femtosecond Laser Measured by Spectral Domain OCT in a Porcine Eye Model

Early Dry Eye Disease Onset in a NOD.H-2 h4 Mouse Model of Sjögren's Syndrome

Lysozyme Protects Against Severe Acute Respiratory Syndrome Coronavirus 2 Infection and Inflammation in Human Corneal Epithelial Cells

Quantitative Assessment of Biomechanical Properties of the Human Keratoconus Cornea Using Acoustic Radiation Force Optical Coherence Elastography

Corneal Epithelium–Derived Netrin-1 Alleviates Dry Eye Disease via Regulating Dendritic Cell Activation

Dynamic Contrast Microscopic Optical Coherence Tomography As a Novel Method for Assessing Corneal Epithelium During Exposure to Benzalkonium Chloride

Scleral Cross-Linking in Form-Deprivation Myopic Guinea Pig Eyes Leads to Glaucomatous Changes

Comprehensive Analysis Identified the Circadian Clock and Global Circadian Gene Expression in Human Corneal Endothelial Cells

Shotgun Proteomics for the Identification and Profiling of the Tear Proteome of Keratoconus Patients

Posttransplant VEGFR1R2 Trap Eye Drops Inhibit Corneal (Lymph)angiogenesis and Improve Corneal Allograft Survival in Eyes at High Risk of Rejection

Melatonin Attenuates LPS-Induced Proinflammatory Cytokine Response and Lipogenesis in Human Meibomian Gland Epithelial Cells via MAPK/NF-κB Pathway

Tear Strip Meniscometry and Its Clinical Application: Analysis of More Than 2000 Cases

Limbal Niche Cells and Three-Dimensional Matrigel-Induced Dedifferentiation of Mature Corneal Epithelial Cells

Repressed miR-34a Expression Dictates the Cell Fate to Corneal Endothelium Failure

Analysis of MicroRNA Expression in Tears of Patients with Herpes Epithelial Keratitis: A Preliminary Study

Forkhead Domain Inhibitor-6 Suppresses Corneal Neovascularization and Subsequent Fibrosis After Alkali Burn in Rats

Prediction of Subjective Refraction From Anterior Corneal Surface, Eye Lengths, and Age Using Machine Learning Algorithms

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