External Eye Disease

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Cornea March 2023

Aim2 Deficiency Ameliorates Lacrimal Gland Destruction and Corneal Epithelium Defects in an Experimental Dry Eye Model

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Yu Chen; Jiheng Pu; Xinda Li; Lili Lian; Chaoxiang Ge; Zuimeng Liu; Weizhuo Wang; Ling Hou; Wei Chen; Jinyang Li
TAGS: corneal epithelium, dry eye syndromes, lacrimal gland, mice, dna, immunohistochemistry, cornea, interleukin-18
Invest. Ophthalmol. Vis. Sci.. 2023; 64(3):26. doi: https://doi.org/10.1167/iovs.64.3.26

Includes: Supplemental Content

Immunology and Microbiology March 2023

T-Cell Repertoire Analysis in the Conjunctiva of Murine Dry Eye Model

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Xiaorui Bao; Yanlin Zhong; Chunyan Yang; Yujie Chen; Yi Han; Xiang Lin; Caihong Huang; Kejia Wang; Zuguo Liu; Cheng Li
TAGS: conjunctiva, dry eye syndromes, mice, t-lymphocytes
Invest. Ophthalmol. Vis. Sci.. 2023; 64(3):14. doi: https://doi.org/10.1167/iovs.64.3.14

Includes: Supplemental Content

Cornea January 2023

Association of Tear Osmolarity With Signs and Symptoms of Dry Eye Disease in the Dry Eye Assessment and Management (DREAM) Study

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Jack V. Greiner; Gui-shuang Ying; Maxwell Pistilli; Maureen G. Maguire; Penny A. Asbell; for the Dry Eye Assessment and Management (DREAM) Study Research Group
TAGS: dreams, dry eye syndromes, osmolar concentration, signs and symptoms
Invest. Ophthalmol. Vis. Sci.. 2023; 64(1):5. doi: https://doi.org/10.1167/iovs.64.1.5

Includes: Supplemental Content

Lacrimal Apparatus, Eyelids, Orbit January 2023

Establishment of a Beagle Dog Model of Dry Eye Disease

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Zhi-zheng Li; Yan-ping Zou; Hui Zhu; Wei-zhen Zeng; Yi Ding; Jia-zeng Su; Guang-yan Yu
TAGS: cornea, dog, domestic, dry eye syndromes, eye, molecule, surgical procedures, operative, fluorescein stain method, conjunctiva, ocular surfaces, bodily secretions
Trans. Vis. Sci. Tech.. 2023; 12(1):2. doi: https://doi.org/10.1167/tvst.12.1.2

Immunology and Microbiology December 2022

Microbiological Characteristics of Ocular Surface Associated With Dry Eye in Children and Adolescents With Diabetes Mellitus

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Zhangling Chen; Yan Jia; Ying Xiao; Qiurong Lin; Yu Qian; Zhaoyu Xiang; Lipu Cui; Xinran Qin; Shuli Chen; Chenhao Yang; Haidong Zou
TAGS: adolescent, child, diabetes mellitus, dry eye syndromes, ocular surfaces, rna, ribosomal, 16s, microorganisms
Invest. Ophthalmol. Vis. Sci.. 2022; 63(13):20. doi: https://doi.org/10.1167/iovs.63.13.20

Cornea & External Disease November 2022

Dry Eye Subtypes in the Dry Eye Assessment and Management (DREAM) Study: A Latent Profile Analysis

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Kimberley Yu; Penny A. Asbell; Roni M. Shtein; Gui-Shuang Ying; for Dry Eye Assessment and Management Study Research Group
TAGS: dreams, dry eye syndromes, signs and symptoms, omega-3 fatty acids
Trans. Vis. Sci. Tech.. 2022; 11(11):13. doi: https://doi.org/10.1167/tvst.11.11.13

Includes: Supplemental Content

Cornea November 2022

AMPK/MFF Activation: Role in Mitochondrial Fission and Mitophagy in Dry Eye

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Fangli Peng; Dan Jiang; Wei Xu; Yining Sun; Zhiwei Zha; Xiying Tan; Jinjie Yu; Chengjie Pan; Qinxiang Zheng; Wei Chen
TAGS: ampk, dry eye syndromes, mitochondria
Invest. Ophthalmol. Vis. Sci.. 2022; 63(12):18. doi: https://doi.org/10.1167/iovs.63.12.18

Includes: Supplemental Content

Cornea November 2022

Conjunctiva Resident γδ T Cells Expressed High Level of IL-17A and Promoted the Severity of Dry Eye

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Ling Li; Yanxiao Li; Xinhao Zhu; Biao Wu; Zhuo Tang; Han Wen; Jianshu Yuan; Qinxiang Zheng; Wei Chen
TAGS: conjunctiva, dry eye syndromes, interleukin-17, mice, t-lymphocytes, ocular surfaces, internship and residency, medical residencies
Invest. Ophthalmol. Vis. Sci.. 2022; 63(12):13. doi: https://doi.org/10.1167/iovs.63.12.13

Includes: Supplemental Content

Cornea & External Disease October 2022

Feasibility of Magnetic Levator Prosthesis Frame Customization Using Craniofacial Scans and 3-D Printing

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Kevin E. Houston; Eleftherios I. Paschalis
TAGS: benchmarking, eye, magnets, printing, three-dimensional, prostheses, fissure, eyelid, face
Trans. Vis. Sci. Tech.. 2022; 11(10):34. doi: https://doi.org/10.1167/tvst.11.10.34

Cornea & External Disease October 2022

Corneal Neuro-Regenerative Effect of Transcutaneous Electrical Stimulation in Rabbit Lamellar Keratectomy Model

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Young-Sik Yoo; Sera Park; Pyeonghwa Eun; Young Min Park; Dong Hui Lim; Tae-Young Chung
TAGS: cornea, electric stimulation, keratectomy, oryctolagus cuniculus, superior limbic keratoconjunctivitis, transcutaneous electric nerve stimulation, proteins, wound healing
Trans. Vis. Sci. Tech.. 2022; 11(10):17. doi: https://doi.org/10.1167/tvst.11.10.17

Cornea & External Disease October 2022

The Therapeutic Effects of a PEDF-Derived Short Peptide on Murine Experimental Dry Eye Involves Suppression of MMP-9 and Inflammation

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Tsung-Chuan Ho; Nai-Wen Fan; Shu-I Yeh; Show-Li Chen; Yeou-Ping Tsao
TAGS: dry eye syndromes, gelatinase b, inflammation, mice, peptides, cornea, ocular surfaces
Trans. Vis. Sci. Tech.. 2022; 11(10):12. doi: https://doi.org/10.1167/tvst.11.10.12

Cornea & External Disease September 2022

Effect of Recombinant Human Lubricin on Model Tear Film Stability

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Kiara W. Cui; Vincent X. Xia; Daniel Cirera-Salinas; David Myung; Gerald G. Fuller
TAGS: tear film finding
Trans. Vis. Sci. Tech.. 2022; 11(9):9. doi: https://doi.org/10.1167/tvst.11.9.9

Includes: Multimedia, Supplemental Content

Cornea September 2022

AKR1C1 Protects Corneal Epithelial Cells Against Oxidative Stress-Mediated Ferroptosis in Dry Eye

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Xin Zuo; Hao Zeng; Bowen Wang; Xue Yang; Dalian He; Li Wang; Hong Ouyang; Jin Yuan
TAGS: corneal epithelial cells, dry eye syndromes, ferroptosis, stress
Invest. Ophthalmol. Vis. Sci.. 2022; 63(10):3. doi: https://doi.org/10.1167/iovs.63.10.3

Includes: Supplemental Content

Cornea & External Disease July 2022

Virulence Genes of Staphylococcus aureus Associated With Keratitis, Conjunctivitis, and Contact Lens–Associated Inflammation

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Madeeha Afzal; Ajay Kumar Vijay; Fiona Stapleton; Mark Willcox
TAGS: conjunctivitis, contact lenses, genes, inflammation, keratitis, virulence, staphylococcus aureus, infections, virulence factors
Trans. Vis. Sci. Tech.. 2022; 11(7):5. doi: https://doi.org/10.1167/tvst.11.7.5

Includes: Supplemental Content

Biochemistry and Molecular Biology June 2022

Early Dry Eye Disease Onset in a NOD.H-2 h4 Mouse Model of Sjögren's Syndrome

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Lili Li; Kimberly J. Jasmer; Jean M. Camden; Lucas T. Woods; Adam L. Martin; Yong Yang; Maria Layton; Michael J. Petris; Olga J. Baker; Gary A. Weisman; Carisa K. Petris
TAGS: mice, dry eye syndromes, sjogren's syndrome
Invest. Ophthalmol. Vis. Sci.. 2022; 63(6):18. doi: https://doi.org/10.1167/iovs.63.6.18

Includes: Supplemental Content

Immunology and Microbiology June 2022

PPAR-α Agonist Fenofibrate Ameliorates Sjögren Syndrome–Like Dacryoadenitis by Modulating Th1/Th17 and Treg Cell Responses in NOD Mice

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Xingyi Guo; Weiyu Dang; Na Li; Ying Wang; Deming Sun; Hong Nian; Ruihua Wei
TAGS: dacryoadenitis, dry eye syndromes, fenofibrate, peroxisome proliferator-activated receptors, regulatory t-lymphocytes, mice, inbred nod, sjogren's syndrome, agonists
Invest. Ophthalmol. Vis. Sci.. 2022; 63(6):12. doi: https://doi.org/10.1167/iovs.63.6.12

Includes: Supplemental Content

Cornea June 2022

Corneal Epithelium–Derived Netrin-1 Alleviates Dry Eye Disease via Regulating Dendritic Cell Activation

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Chaoqun Yu; Peng Chen; Jing Xu; Susu Wei; Qilong Cao; Chuanlong Guo; Xianggen Wu; Guohu Di
TAGS: cornea, corneal epithelium, dendritic cells, dry eye syndromes, mice, netrin-1, regulation, antibodies
Invest. Ophthalmol. Vis. Sci.. 2022; 63(6):1. doi: https://doi.org/10.1167/iovs.63.6.1

Cornea May 2022

Melatonin Attenuates LPS-Induced Proinflammatory Cytokine Response and Lipogenesis in Human Meibomian Gland Epithelial Cells via MAPK/NF-κB Pathway

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Ren Liu; Jing Li; Yue Xu; Ziyan Chen; Huijing Ye; Jinhui Tang; Lai Wei; Lingyi Liang
TAGS: cytokine, epithelial cells, lipogenesis, meibomian gland, melatonin, mitogen-activated protein kinases, proteins, toll-like receptor 4
Invest. Ophthalmol. Vis. Sci.. 2022; 63(5):6. doi: https://doi.org/10.1167/iovs.63.5.6

Includes: Supplemental Content

Articles May 2022

Tear Strip Meniscometry and Its Clinical Application: Analysis of More Than 2000 Cases

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Keiichi Miyasaka; Masahiko Ayaki; Kazuno Negishi
TAGS: cornea, dry eye syndromes, fluorescein stain method, ocular surfaces, pain, schirmer tear test procedure, signs and symptoms, roc curve, joint meniscus, fluorescein
Trans. Vis. Sci. Tech.. 2022; 11(5):3. doi: https://doi.org/10.1167/tvst.11.5.3

Includes: Supplemental Content

Biochemistry and Molecular Biology May 2022

The Protective Effects of KAT5 Inhibition on Ocular Inflammation by Mediating the PI3K/AKT Pathway in a Murine Model of Allergic Conjunctivitis

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Fei Luo; Yu Tao; Mengyu Wang; Liuqing Yang; Ruifeng Su; Zhiqiang Pan; Xiaobo Tan
TAGS: 1-phosphatidylinositol 3-kinase, mice, phosphoinositide 3-kinase, eye inflammation, protein overexpression, allergic conjunctivitis, inflammatory response, proto-oncogene proteins c-akt, phenotype, akt signaling pathway
Invest. Ophthalmol. Vis. Sci.. 2022; 63(5):4. doi: https://doi.org/10.1167/iovs.63.5.4

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Aim2 Deficiency Ameliorates Lacrimal Gland Destruction and Corneal Epithelium Defects in an Experimental Dry Eye Model

T-Cell Repertoire Analysis in the Conjunctiva of Murine Dry Eye Model

Association of Tear Osmolarity With Signs and Symptoms of Dry Eye Disease in the Dry Eye Assessment and Management (DREAM) Study

Establishment of a Beagle Dog Model of Dry Eye Disease

Microbiological Characteristics of Ocular Surface Associated With Dry Eye in Children and Adolescents With Diabetes Mellitus

Dry Eye Subtypes in the Dry Eye Assessment and Management (DREAM) Study: A Latent Profile Analysis

AMPK/MFF Activation: Role in Mitochondrial Fission and Mitophagy in Dry Eye

Conjunctiva Resident γδ T Cells Expressed High Level of IL-17A and Promoted the Severity of Dry Eye

Feasibility of Magnetic Levator Prosthesis Frame Customization Using Craniofacial Scans and 3-D Printing

Corneal Neuro-Regenerative Effect of Transcutaneous Electrical Stimulation in Rabbit Lamellar Keratectomy Model

The Therapeutic Effects of a PEDF-Derived Short Peptide on Murine Experimental Dry Eye Involves Suppression of MMP-9 and Inflammation

Effect of Recombinant Human Lubricin on Model Tear Film Stability

AKR1C1 Protects Corneal Epithelial Cells Against Oxidative Stress-Mediated Ferroptosis in Dry Eye

Virulence Genes of Staphylococcus aureus Associated With Keratitis, Conjunctivitis, and Contact Lens–Associated Inflammation

Early Dry Eye Disease Onset in a NOD.H-2 h4 Mouse Model of Sjögren's Syndrome

PPAR-α Agonist Fenofibrate Ameliorates Sjögren Syndrome–Like Dacryoadenitis by Modulating Th1/Th17 and Treg Cell Responses in NOD Mice

Corneal Epithelium–Derived Netrin-1 Alleviates Dry Eye Disease via Regulating Dendritic Cell Activation

Melatonin Attenuates LPS-Induced Proinflammatory Cytokine Response and Lipogenesis in Human Meibomian Gland Epithelial Cells via MAPK/NF-κB Pathway

Tear Strip Meniscometry and Its Clinical Application: Analysis of More Than 2000 Cases

The Protective Effects of KAT5 Inhibition on Ocular Inflammation by Mediating the PI3K/AKT Pathway in a Murine Model of Allergic Conjunctivitis

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