Immunology and Microbiology

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Biochemistry and Molecular Biology June 2017

Identification of Novel G Protein–Coupled Receptor 143 Ligands as Pharmacologic Tools for Investigating X-Linked Ocular Albinism

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Elisabetta De Filippo; Prashiela Manga; Anke C. Schiedel
TAGS: albinism, ocular, arrestin, chinese hamster ovary cell, ethacridine, lactates, levodopa, ligands, melanins, melanocyte, monophenol monooxygenase, niclosamide, pimozide, pharmacology, proteins, g-protein-coupled receptors, x-linked inheritance, screening, lysate
Invest. Ophthalmol. Vis. Sci.. 2017; 58(7):3118-3126. doi: 10.1167/iovs.16-21128

Includes: Supplemental Content

Retinal Cell Biology June 2017

Complement-Mediated Regulation of Apolipoprotein E in Cultured Human RPE Cells

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Ping Yang; Nikolai P. Skiba; Grace M. Tewkesbury; Victoria M. Treboschi; Peter Baciu; Glenn J. Jaffe
TAGS: apolipoprotein e, complement system proteins, complement membrane attack complex, proteins, retinal pigment cell
Invest. Ophthalmol. Vis. Sci.. 2017; 58(7):3073-3085. doi: 10.1167/iovs.16-20083

Includes: Supplemental Content

Cornea June 2017

Rat Limbal Niche Cells Prevent Epithelial Stem/Progenitor Cells From Differentiation and Proliferation by Inhibiting Notch Signaling Pathway In Vitro

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Jing Li; Szu-Yu Chen; Xin-Yue Zhao; Ming-Chang Zhang; Hua-Tao Xie
TAGS: signal transduction, western blotting, stem cells, epithelium, ligands, cornea, notch signaling pathway, dual antiplatelet therapy
Invest. Ophthalmol. Vis. Sci.. 2017; 58(7):2968-2976. doi: 10.1167/iovs.16-20642

Includes: Supplemental Content

Retinal Cell Biology June 2017

Retinal Macrophages Synthesize C3 and Activate Complement in AMD and in Models of Focal Retinal Degeneration

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Riccardo Natoli; Nilisha Fernando; Haihan Jiao; Tanja Racic; Michele Madigan; Nigel L. Barnett; Joshua A. Chu-Tan; Krisztina Valter; Jan Provis; Matt Rutar
TAGS: atrophy, complement system proteins, macrophage, retinal degeneration, mice, retina, rna, small interfering
Invest. Ophthalmol. Vis. Sci.. 2017; 58(7):2977-2990. doi: 10.1167/iovs.17-21672

Includes: Supplemental Content

Retinal Cell Biology June 2017

Overexpression of Angiotensin-Converting Enzyme 2 Ameliorates Amyloid β-Induced Inflammatory Response in Human Primary Retinal Pigment Epithelium

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Xinyu Fu; Ru Lin; Yiguo Qiu; Peng Yu; Bo Lei
TAGS: amyloid, apoptosis, cytokine, polymerase chain reaction, enzyme-linked immunosorbent assay, angiotensin-converting enzyme, inflammation, plasmids, monocyte chemoattractant protein-1, rna, messenger, proteins, antagonists, inflammatory response, protein overexpression, retinal pigment epithelium, retinal pigment cell
Invest. Ophthalmol. Vis. Sci.. 2017; 58(7):3018-3028. doi: 10.1167/iovs.17-21546

Article June 2017

Temporal brightness illusion changes color perception of “the dress”

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Laila Hugrass; Jana Slavikova; Melissa Horvat; Alaa Al Musawi; David Crewther
TAGS: color, color perception, illusions, hypersensitivity syndrome, drug-induced
Journal of Vision. 2017; 17(5):6. doi: 10.1167/17.5.6

Includes: Multimedia, Supplemental Content

Article June 2017

Illumination assumptions account for individual differences in the perceptual interpretation of a profoundly ambiguous stimulus in the color domain: “The dress”

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Pascal Wallisch
TAGS: color, lighting, hypersensitivity syndrome, drug-induced
Journal of Vision. 2017; 17(4):5. doi: 10.1167/17.4.5

Visual Neuroscience June 2017

Autoantibodies in Melanoma-Associated Retinopathy Recognize an Epitope Conserved Between TRPM1 and TRPM3

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Robert M. Duvoisin; Tammie L. Haley; Gaoying Ren; Iwona Strycharska-Orczyk; James P. Bonaparte; Catherine W. Morgans
TAGS: autoantibodies, epitopes, antibodies, retinopathy, melanoma associated, serum
Invest. Ophthalmol. Vis. Sci.. 2017; 58(5):2732-2738. doi: 10.1167/iovs.17-21443

Cornea June 2017

ISG15 in Host Defense Against Candida albicans Infection in a Mouse Model of Fungal Keratitis

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Chen Dong; Nan Gao; Bing X. Ross; Fu-Shin X. Yu
TAGS: candida albicans, flagellin, infection, cornea, mice, host defense, keratitis, fungal, chronic exertional compartment syndrome
Invest. Ophthalmol. Vis. Sci.. 2017; 58(7):2948-2958. doi: 10.1167/iovs.17-21476

Clinical and Epidemiologic Research June 2017

Effect of Mandarin Orange Yogurt on Allergic Conjunctivitis Induced by Conjunctival Allergen Challenge

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Yuko Hara; Atsushi Shiraishi; Yuri Sakane; Yuki Takezawa; Tomoyuki Kamao; Yuichi Ohashi; Sho Yasunaga; Takuya Sugahara
TAGS: conjunctivitis, allergens, allergic conjunctivitis, yogurt, body temperature, conjunctiva, temperature, mandarin
Invest. Ophthalmol. Vis. Sci.. 2017; 58(7):2922-2929. doi: 10.1167/iovs.16-21206

Cornea June 2017

SERPINA3K Ameliorates the Corneal Oxidative Injury Induced by 4-Hydroxynonenal

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Xiling Zheng; Huixia Cui; Yuanyuan Yin; Yajing Zhang; Rongrong Zong; Xiaorui Bao; Jian-xing Ma; Zuguo Liu; Yueping Zhou
TAGS: antioxidants, western blotting, oxidants, wounds and injuries, cornea
Invest. Ophthalmol. Vis. Sci.. 2017; 58(7):2874-2883. doi: 10.1167/iovs.17-21544

Article June 2017

Exploring the spatio-temporal neural basis of face learning

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Ying Yang; Yang Xu; Carol A. Jew; John A. Pyles; Robert E. Kass; Michael J. Tarr
TAGS: face, learning, sensor
Journal of Vision. 2017; 17(6):1. doi: 10.1167/17.6.1

Includes: Supplemental Content

Cornea May 2017

KLF4 Plays an Essential Role in Corneal Epithelial Homeostasis by Promoting Epithelial Cell Fate and Suppressing Epithelial–Mesenchymal Transition

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Anil Tiwari; Chelsea L. Loughner; Sudha Swamynathan; Shivalingappa K. Swamynathan
TAGS: epithelium, homeostasis, cyclin d1, antibodies, cornea, survivin, epithelial cells, e-cadherin, epithelial to mesenchymal transition
Invest. Ophthalmol. Vis. Sci.. 2017; 58(5):2785-2795. doi: 10.1167/iovs.17-21826

Includes: Supplemental Content

Immunology and Microbiology May 2017

Cytokines and Chemokines Involved in Acute Retinal Necrosis

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L. de Visser; J.H. de Boer; G.T. Rijkers; K. Wiertz; H.J. van den Ham; R. de Boer; A.M. van Loon; A. Rothova; D. F. de Groot-Mijnes
TAGS: cytokine, chemokine, retinal necrosis syndrome, acute, immune mediator
Invest. Ophthalmol. Vis. Sci.. 2017; 58(4):2139-2151. doi: 10.1167/iovs.16-20799

Cornea May 2017

Xeno-Free Cultivation of Mesenchymal Stem Cells From the Corneal Stroma

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Steffi Matthyssen; Sorcha Ní Dhubhghaill; Veerle Van Gerwen; Nadia Zakaria
TAGS: flow cytometry, cell size, corneal stroma, cornea, stem cell, mesenchymal, donors
Invest. Ophthalmol. Vis. Sci.. 2017; 58(5):2659-2665. doi: 10.1167/iovs.17-21676

Clinical and Epidemiologic Research May 2017

Radiologic Parameters of Orbital Bone Remodeling in Thyroid Eye Disease

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Nicholas Y. Q. Tan; Yuan-Yuh Leong; Stephanie S. Lang; Zin M. Htoon; Stephanie M. Young; Gangadhara Sundar
TAGS: computed tomography, graves' ophthalmopathy, muscle of orbit, orbit, radiology specialty, zygomatic bone, medial rectus muscle, volume
Invest. Ophthalmol. Vis. Sci.. 2017; 58(5):2527-2533. doi: 10.1167/iovs.16-21035

Special Issue May 2017

The Growing Need for Validated Biomarkers and Endpoints for Dry Eye Clinical Research

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Neeta S. Roy; Yi Wei; Eric Kuklinski; Penny A. Asbell
TAGS: biological markers, dry eye syndromes, surrogate endpoints, clinical research
Invest. Ophthalmol. Vis. Sci.. 2017; 58(6):BIO1-BIO19. doi: 10.1167/iovs.17-21709

Special Issue May 2017

Iris Damage Is Associated With Elevated Cytokine Levels in Aqueous Humor

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Naohiko Aketa; Takefumi Yamaguchi; Terumasa Suzuki; Kazunari Higa; Yukari Yagi-Yaguchi; Yoshiyuki Satake; Kazuo Tsubota; Jun Shimazaki
TAGS: cytokine, eye, iris, proteins, immune reconstitution inflammatory syndrome
Invest. Ophthalmol. Vis. Sci.. 2017; 58(6):BIO42-BIO51. doi: 10.1167/iovs.17-21421

Includes: Supplemental Content

Special Issue May 2017

Cibinetide Improves Corneal Nerve Fiber Abundance in Patients With Sarcoidosis-Associated Small Nerve Fiber Loss and Neuropathic Pain

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Daniel A. Culver; Albert Dahan; Daiva Bajorunas; Maria Jeziorska; Monique van Velzen; Leon P. H. J. Aarts; Jinny Tavee; Martijn R. Tannemaat; Ann N. Dunne; Rita I. Kirk; Ioannis N. Petropoulos; Anthony Cerami; Rayaz A. Malik; Michael Brines
TAGS: sarcoidosis, growth associated protein 43, nerve fibers, pain, placebos, cornea, neuropathic pain, neuropathy, small-fiber
Invest. Ophthalmol. Vis. Sci.. 2017; 58(6):BIO52-BIO60. doi: 10.1167/iovs.16-21291

Includes: Supplemental Content

Clinical and Epidemiologic Research May 2017

Progressive Retinal Vasodilation in Patients With Type 1 Diabetes: A Longitudinal Study of Retinal Vascular Geometry

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Gerald Liew; Paul Benitez-Aguirre; Maria E. Craig; Alicia J. Jenkins; Lauren A. B. Hodgson; Annette Kifley; Paul Mitchell; Tien Y. Wong; Kim Donaghue
TAGS: diabetes mellitus, type 1, diabetic retinopathy, hemoglobin a, glycosylated, longitudinal studies, retinal diseases, vasodilation, diameter
Invest. Ophthalmol. Vis. Sci.. 2017; 58(5):2503-2509. doi: 10.1167/iovs.16-21015

Includes: Supplemental Content

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Identification of Novel G Protein–Coupled Receptor 143 Ligands as Pharmacologic Tools for Investigating X-Linked Ocular Albinism

Complement-Mediated Regulation of Apolipoprotein E in Cultured Human RPE Cells

Rat Limbal Niche Cells Prevent Epithelial Stem/Progenitor Cells From Differentiation and Proliferation by Inhibiting Notch Signaling Pathway In Vitro

Retinal Macrophages Synthesize C3 and Activate Complement in AMD and in Models of Focal Retinal Degeneration

Overexpression of Angiotensin-Converting Enzyme 2 Ameliorates Amyloid β-Induced Inflammatory Response in Human Primary Retinal Pigment Epithelium

Temporal brightness illusion changes color perception of “the dress”

Illumination assumptions account for individual differences in the perceptual interpretation of a profoundly ambiguous stimulus in the color domain: “The dress”

Autoantibodies in Melanoma-Associated Retinopathy Recognize an Epitope Conserved Between TRPM1 and TRPM3

ISG15 in Host Defense Against Candida albicans Infection in a Mouse Model of Fungal Keratitis

Effect of Mandarin Orange Yogurt on Allergic Conjunctivitis Induced by Conjunctival Allergen Challenge

SERPINA3K Ameliorates the Corneal Oxidative Injury Induced by 4-Hydroxynonenal

Exploring the spatio-temporal neural basis of face learning

KLF4 Plays an Essential Role in Corneal Epithelial Homeostasis by Promoting Epithelial Cell Fate and Suppressing Epithelial–Mesenchymal Transition

Cytokines and Chemokines Involved in Acute Retinal Necrosis

Xeno-Free Cultivation of Mesenchymal Stem Cells From the Corneal Stroma

Radiologic Parameters of Orbital Bone Remodeling in Thyroid Eye Disease

The Growing Need for Validated Biomarkers and Endpoints for Dry Eye Clinical Research

Iris Damage Is Associated With Elevated Cytokine Levels in Aqueous Humor

Cibinetide Improves Corneal Nerve Fiber Abundance in Patients With Sarcoidosis-Associated Small Nerve Fiber Loss and Neuropathic Pain

Progressive Retinal Vasodilation in Patients With Type 1 Diabetes: A Longitudinal Study of Retinal Vascular Geometry

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