Immunology and Microbiology

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Article December 2019

Interocular difference thresholds are mediated by binocular differencing, not summing, channels

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Frederick A. A. Kingdom; Nour M. Seulami; Ben J. Jennings; Mark A. Georgeson
TAGS: clostridium difficile, transducers, health disparity, eye, luminance
Journal of Vision. 2019; 19(14):18. doi: https://doi.org/10.1167/19.14.18

Retinal Cell Biology December 2019

The Interplay Between E-Cadherin, Connexin 43, and Zona Occludens 1 in Retinal Pigment Epithelial Cells

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Huiqian Bao; Shuai Yang; Hui Li; Haipei Yao; Yao Zhang; Jingfa Zhang; Guotong Xu; Haiying Jin; Fang Wang
TAGS: connexin 43, e-cadherin, herpes zoster disease
Invest. Ophthalmol. Vis. Sci.. 2019; 60(15):5104-5111. doi: https://doi.org/10.1167/iovs.19-27768

Retina December 2019

Monocyte-Derived Macrophages Are Necessary for Beta-Adrenergic Receptor-Driven Choroidal Neovascularization Inhibition

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Steven Droho; Carla M. Cuda; Harris Perlman; Jeremy A. Lavine
TAGS: choroidal neovascularization, lasers, macrophages, mice, propranolol, monocytes
Invest. Ophthalmol. Vis. Sci.. 2019; 60(15):5059-5069. doi: https://doi.org/10.1167/iovs.19-28165

Includes: Supplemental Content

Immunology and Microbiology December 2019

VISTA Is Crucial for Corneal Allograft Survival and Maintenance of Immune Privilege

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Tomoyuki Kunishige; Hiroko Taniguchi; Tatsukuni Ohno; Miyuki Azuma; Junko Hori
TAGS: allografting, cornea, immune privilege, monoclonal antibodies, t-lymphocytes, mice, immunoglobulin g, eye
Invest. Ophthalmol. Vis. Sci.. 2019; 60(15):4958-4965. doi: https://doi.org/10.1167/iovs.19-27322

Includes: Supplemental Content

Genetics November 2019

Replication of Genome-Wide Association Analysis Identifies New Susceptibility Loci at Long Noncoding RNA Regions for Vogt-Koyanagi-Harada Disease

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Jian Qi; Liping Du; Jing Deng; Yang Qin; Guannan Su; Shengping Hou; Meng Lv; Qi Zhang; Aize Kijlstra; Peizeng Yang
TAGS: cytokine, disease susceptibility, genome-wide association study, genotype, rna, messenger, rna, untranslated, single nucleotide polymorphism, uveomeningoencephalitic syndrome, chief complaint
Invest. Ophthalmol. Vis. Sci.. 2019; 60(14):4820-4829. doi: https://doi.org/10.1167/iovs.19-27708

Lecture November 2019

Introducing Sheila K. West, the Recipient of the 2019 Weisenfeld Award

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Alfred Sommer
TAGS: awards and prizes
Invest. Ophthalmol. Vis. Sci.. 2019; 60(14):4803-4804. doi: https://doi.org/10.1167/iovs.19-28630

Immunology and Microbiology November 2019

Neutrophil Activities in Human Ocular Toxoplasmosis: An In Vitro Study With Human Cells

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Liam M. Ashander; Shervi Lie; Yuefang Ma; Elise Rochet; Jennifer M. Washington; João M. Furtado; Binoy Appukuttan; Justine R. Smith
TAGS: neutrophils, ocular toxoplasmosis, infection, retinal pigment cell
Invest. Ophthalmol. Vis. Sci.. 2019; 60(14):4652-4660. doi: https://doi.org/10.1167/iovs.19-28306

Includes: Supplemental Content

Biochemistry and Molecular Biology November 2019

LncRNA PLCD3-OT1 Functions as a CeRNA to Prevent Age-Related Cataract by Sponging miR-224-5p and Regulating PLCD3 Expression

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Jing Xiang; Qin Chen; Lihua Kang; Guowei Zhang; Yong Wang; Bai Qin; Jian Wu; Tianqiu Zhou; Yongzhao Han; Huaijin Guan
TAGS: apoptosis, cataract, senile, cell cycle, polymerase chain reaction, protein overexpression, proteins, rna, rna, messenger, ultraviolet b radiation, cell survival
Invest. Ophthalmol. Vis. Sci.. 2019; 60(14):4670-4680. doi: https://doi.org/10.1167/iovs.19-27211

Includes: Supplemental Content

Articles November 2019

The Role of Meibography in the Diagnosis of Meibomian Gland Dysfunction in Ocular Surface Diseases

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Mathieu Robin; Hong Liang; Ghislaine Rabut; Edouard Augstburger; Christophe Baudouin; Antoine Labbé
TAGS: meibomian gland, pathophysiology, hypersensitivity, schirmer tear test procedure, signs and symptoms
Trans. Vis. Sci. Tech.. 2019; 8(6):6. doi: https://doi.org/10.1167/tvst.8.6.6

Physiology and Pharmacology November 2019

Propranolol Attenuates Proangiogenic Activity of Mononuclear Phagocytes: Implication in Choroidal Neovascularization

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Samy Omri; Houda Tahiri; Wyston Chadwick Pierre; Michel Desjarlais; Isabelle Lahaie; Sarah-Eve Loiselle; Flavio Rezende; Gregory Lodygensky; Terence E. Hebert; Huy Ong; Sylvain Chemtob
TAGS: choroidal neovascularization, propranolol, reticuloendothelial system, macrophages, angiogenesis
Invest. Ophthalmol. Vis. Sci.. 2019; 60(14):4632-4642. doi: https://doi.org/10.1167/iovs.18-25502

Includes: Supplemental Content

Biochemistry and Molecular Biology November 2019

Characterization of LSD1 Expression Within the Murine Eye

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Salma Ferdous; Hans E. Grossniklaus; Jeffrey H. Boatright; John M. Nickerson
TAGS: eye, mice, proteins, retina
Invest. Ophthalmol. Vis. Sci.. 2019; 60(14):4619-4631. doi: https://doi.org/10.1167/iovs.19-26728

Includes: Supplemental Content

Biochemistry and Molecular Biology November 2019

Chitinase-3-Like-1 Promotes M2 Macrophage Differentiation and Induces Choroidal Neovascularization in Neovascular Age-Related Macular Degeneration

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Nana Xu; Qiyu Bo; Rong Shao; Jian Liang; Yuanqi Zhai; Shiqi Yang; Fenghua Wang; Xiaodong Sun
TAGS: chitinase-3-like protein 1, choroidal neovascularization, macrophages, angiogenesis, exudative age-related macular degeneration, chitinases
Invest. Ophthalmol. Vis. Sci.. 2019; 60(14):4596-4605. doi: https://doi.org/10.1167/iovs.19-27493

Includes: Supplemental Content

Cornea November 2019

Graft Versus Host Disease-Associated Dry Eye: Role of Ocular Surface Mucins and the Effect of Rebamipide, a Mucin Secretagogue

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Kiumars Shamloo; Ashley Barbarino; Saleh Alfuraih; Ajay Sharma
TAGS: cornea, dry eye syndromes, graft-versus-host disease, mucins, rebamipide, secretagogues, mice, tissue transplants, tear film finding, transplantation, homologous
Invest. Ophthalmol. Vis. Sci.. 2019; 60(14):4511-4519. doi: https://doi.org/10.1167/iovs.19-27843

Immunology and Microbiology November 2019

Composition and Diversity of Bacterial Community on the Ocular Surface of Patients With Meibomian Gland Dysfunction

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Xiaojin Dong; Yuqian Wang; Weina Wang; Ping Lin; Yusen Huang
TAGS: meibomian gland dysfunction, microbiome, community, conjunctival sac
Invest. Ophthalmol. Vis. Sci.. 2019; 60(14):4774-4783. doi: https://doi.org/10.1167/iovs.19-27719

Includes: Supplemental Content

Lecture October 2019

The Eye Sees Eye to Eye With the Immune System: The 2019 Proctor Lecture

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Jerry Y. Niederkorn
TAGS: cornea, eye, immune privilege, immune system, nerve ablation, allografting, mice
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4489-4495. doi: https://doi.org/10.1167/iovs.19-28632

Retinal Cell Biology October 2019

Unsaturated Aldehyde Acrolein Promotes Retinal Glial Cell Migration

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Miyuki Murata; Kousuke Noda; Shiho Yoshida; Michiyuki Saito; Akio Fujiya; Atsuhiro Kanda; Susumu Ishida
TAGS: acrolein, chemokine (c-x-c motif) ligand 1, neuroglia, aldehydes
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4425-4435. doi: https://doi.org/10.1167/iovs.19-27346

Includes: Supplemental Content

Retinal Cell Biology October 2019

Creatine is Neuroprotective to Retinal Neurons In Vitro But Not In Vivo

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Paul Ikgan Sia; John P. M. Wood; Glyn Chidlow; Robert Casson
TAGS: creatine
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4360-4377. doi: https://doi.org/10.1167/iovs.18-25858

Includes: Supplemental Content

Glaucoma October 2019

Extracellular Signal-Regulated Kinase 1/2 Pathway Is Insufficiently Involved in the Neuroprotective Effect by Hydrogen Sulfide Supplement in Experimental Glaucoma

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Shouyue Huang; Ping Huang; Huan Yu; Zhongjing Lin; Xiaohong Liu; Xi Shen; Lei Guo; Yisheng Zhong
TAGS: glaucoma, hydrogen sulfide, neuroprotective effect, phosphotransferases, rats, tumor necrosis factors, western blotting, proteins
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4346-4359. doi: https://doi.org/10.1167/iovs.19-27507

Biochemistry and Molecular Biology October 2019

TSHR Signaling Stimulates Proliferation Through PI3K/Akt and Induction of miR-146a and miR-155 in Thyroid Eye Disease Orbital Fibroblasts

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Collynn F. Woeller; Elisa Roztocil; Christine Hammond; Steven E. Feldon
TAGS: micrornas, phosphoinositide 3-kinase, proto-oncogene proteins c-akt, signal transduction, thyrotropin, thyrotropin receptor, fibroblasts, graves' ophthalmopathy
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4336-4345. doi: https://doi.org/10.1167/iovs.19-27865

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology October 2019

Focal Thickness Reduction of the Ganglion Cell-Inner Plexiform Layer Best Discriminates Prior Optic Neuritis in Patients With Multiple Sclerosis

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Huiling Hu; Hong Jiang; Giovana Rosa Gameiro; Jeffrey Hernandez; Silvia Delgado; Jianhua Wang
TAGS: eye, ganglia, maps, medical history, multiple sclerosis, optic neuritis, signs and symptoms
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4257-4269. doi: https://doi.org/10.1167/iovs.19-27574

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Interocular difference thresholds are mediated by binocular differencing, not summing, channels

The Interplay Between E-Cadherin, Connexin 43, and Zona Occludens 1 in Retinal Pigment Epithelial Cells

Monocyte-Derived Macrophages Are Necessary for Beta-Adrenergic Receptor-Driven Choroidal Neovascularization Inhibition

VISTA Is Crucial for Corneal Allograft Survival and Maintenance of Immune Privilege

Replication of Genome-Wide Association Analysis Identifies New Susceptibility Loci at Long Noncoding RNA Regions for Vogt-Koyanagi-Harada Disease

Introducing Sheila K. West, the Recipient of the 2019 Weisenfeld Award

Neutrophil Activities in Human Ocular Toxoplasmosis: An In Vitro Study With Human Cells

LncRNA PLCD3-OT1 Functions as a CeRNA to Prevent Age-Related Cataract by Sponging miR-224-5p and Regulating PLCD3 Expression

The Role of Meibography in the Diagnosis of Meibomian Gland Dysfunction in Ocular Surface Diseases

Propranolol Attenuates Proangiogenic Activity of Mononuclear Phagocytes: Implication in Choroidal Neovascularization

Characterization of LSD1 Expression Within the Murine Eye

Chitinase-3-Like-1 Promotes M2 Macrophage Differentiation and Induces Choroidal Neovascularization in Neovascular Age-Related Macular Degeneration

Graft Versus Host Disease-Associated Dry Eye: Role of Ocular Surface Mucins and the Effect of Rebamipide, a Mucin Secretagogue

Composition and Diversity of Bacterial Community on the Ocular Surface of Patients With Meibomian Gland Dysfunction

The Eye Sees Eye to Eye With the Immune System: The 2019 Proctor Lecture

Unsaturated Aldehyde Acrolein Promotes Retinal Glial Cell Migration

Creatine is Neuroprotective to Retinal Neurons In Vitro But Not In Vivo

Extracellular Signal-Regulated Kinase 1/2 Pathway Is Insufficiently Involved in the Neuroprotective Effect by Hydrogen Sulfide Supplement in Experimental Glaucoma

TSHR Signaling Stimulates Proliferation Through PI3K/Akt and Induction of miR-146a and miR-155 in Thyroid Eye Disease Orbital Fibroblasts

Focal Thickness Reduction of the Ganglion Cell-Inner Plexiform Layer Best Discriminates Prior Optic Neuritis in Patients With Multiple Sclerosis

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