Multidisciplinary Ophthalmic Imaging

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Retina April 2024

Real-Time Temperature-Controlled Retinal Laser Irradiation in Rabbits

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Claus von der Burchard; Christopher Kren; Jan-Erik Fleger; Dirk Theisen-Kunde; Veit Danicke; Hossam S. Abbas; Viktoria Kleyman; Johann Roider; Ralf Brinkmann
TAGS: body temperature, lasers, oryctolagus cuniculus, temperature
Trans. Vis. Sci. Tech.. 2024; 13(4):26. https://doi.org/10.1167/tvst.13.4.26

Includes: Supplemental Content

Visual Psychophysics and Physiological Optics April 2024

Fluorescence Lifetime Imaging of Human Retinal Pigment Epithelium in Pentosan Polysulfate Toxicity Using Adaptive Optics Scanning Light Ophthalmoscopy

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Kristen E. Bowles Johnson; Janet A. H. Tang; Karteek Kunala; Khang T. Huynh; Keith Parkins; Qiang Yang; Jennifer J. Hunter
TAGS: diagnostic imaging, fluorescence, ophthalmoscopy, optics, pentosan sulfuric polyester, retinal pigment epithelium, toxic effect
Invest. Ophthalmol. Vis. Sci.. 2024; 65(4):27. https://doi.org/10.1167/iovs.65.4.27

Artificial Intelligence April 2024

Retinal Fractal Dimension Is a Potential Biomarker for Systemic Health—Evidence From a Mixed-Age, Primary-Care Population

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Justin Engelmann; Stephanie Kearney; Alice McTrusty; Greta McKinlay; Miguel O. Bernabeu; Niall Strang
TAGS: biological markers, fractals, health, image quality, primary health care
Trans. Vis. Sci. Tech.. 2024; 13(4):19. https://doi.org/10.1167/tvst.13.4.19

Includes: Supplemental Content

Anatomy and Pathology/Oncology April 2024

Short-Term Myopic Defocus and Choroidal Thickness in Children and Adults

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Lisa A. Ostrin; Raman P. Sah; Hope M. Queener; Nimesh B. Patel; Raphaella Tran; Divya Shukla; Hanieh Mirhajianmoghadam
TAGS: adult, child, choroid, eye, refractive errors
Invest. Ophthalmol. Vis. Sci.. 2024; 65(4):22. https://doi.org/10.1167/iovs.65.4.22

Clinical and Epidemiologic Research April 2024

Early Single-Examination Optical Coherence Tomography Biomarkers for Treatment-Requiring Retinopathy of Prematurity

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Xi Chen; Shwetha Mangalesh; Jocelyn He; Katrina P. Winter; Vincent Tai; Cynthia A. Toth; Gui-Shuang Ying
TAGS: biological markers, eye, macular edema, optical coherence tomography, retinopathy of prematurity, diagnostic imaging, infant, premature, infant, gestational age, ratio of arterial oxygen tension to inspired oxygen fraction
Invest. Ophthalmol. Vis. Sci.. 2024; 65(4):21. https://doi.org/10.1167/iovs.65.4.21

Includes: Supplemental Content

Retina April 2024

Early Choriocapillaris Loss in a Porcine Model of RPE Cell Debridement Precedes Pathology That Simulates Advanced Macular Degeneration

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Raymond Iezzi; Brittni A. Scruggs; Jarel Gandhi; Francesca N. Zenti; Noah Shafi; Aubrey Berger; Alan D. Marmorstein
TAGS: debridement, macular degeneration, suidae, retinal pigment cell, pathology
Invest. Ophthalmol. Vis. Sci.. 2024; 65(4):8. https://doi.org/10.1167/iovs.65.4.8

Includes: Multimedia, Supplemental Content

Artificial Intelligence April 2024

Deep Learning-Based Automated Detection of Retinal Breaks and Detachments on Fundus Photography

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Merlin Christ; Oussama Habra; Killian Monnin; Kevin Vallotton; Raphael Sznitman; Sebastian Wolf; Martin Zinkernagel; Pablo Márquez Neila
TAGS: deep learning, retinal detachment, retinal perforations, fundus photography, learning
Trans. Vis. Sci. Tech.. 2024; 13(4):1. https://doi.org/10.1167/tvst.13.4.1

Clinical Trials March 2024

OCTA Signal Quality Augmentation Using the Isometric Handgrip Test to Maximize Vascular Flow (SQUEEZE): A Randomized Crossover Trial

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Matt Trinh; Judy Nam; Meenakshi Kumar; Lisa Nivison-Smith
TAGS: vascular flow, eye, grip strength
Trans. Vis. Sci. Tech.. 2024; 13(3):22. https://doi.org/10.1167/tvst.13.3.22

Includes: Supplemental Content

Multidisciplinary Ophthalmic Imaging March 2024

Adaptive Optics Retinal Imaging in RDH12 -Associated Early Onset Severe Retinal Dystrophy

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Malena Daich Varela; Mira Dixit; Angelos Kalitzeos; Michel Michaelides
TAGS: diagnostic imaging, optics, retinal cone, retinal dystrophies, retinal imaging, photoreceptors
Invest. Ophthalmol. Vis. Sci.. 2024; 65(3):9. https://doi.org/10.1167/iovs.65.3.9

Includes: Supplemental Content

Artificial Intelligence March 2024

RobOCTNet: Robotics and Deep Learning for Referable Posterior Segment Pathology Detection in an Emergency Department Population

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Ailin Song; Jay B. Lusk; Kyung-Min Roh; S. Tammy Hsu; Nita G. Valikodath; Eleonora M. Lad; Kelly W. Muir; Matthew M. Engelhard; Alexander T. Limkakeng; Joseph A. Izatt; Ryan P. McNabb; Anthony N. Kuo
TAGS: deep learning, emergency service, hospital, pathology, robotics, training, eye
Trans. Vis. Sci. Tech.. 2024; 13(3):12. https://doi.org/10.1167/tvst.13.3.12

Includes: Multimedia, Supplemental Content

Multidisciplinary Ophthalmic Imaging March 2024

Acetazolamide Challenge Changes Outer Retina Bioenergy-Linked and Anatomical OCT Biomarkers Depending on Mouse Strain

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Bruce A. Berkowitz; Anuhya Paruchuri; Josh Stanek; Robert H. Podolsky; Karen Lins Childers; Robin Roberts
TAGS: acetazolamide, biological markers, mice, mitochondria, retina, rod photoreceptors
Invest. Ophthalmol. Vis. Sci.. 2024; 65(3):21. https://doi.org/10.1167/iovs.65.3.21

Multidisciplinary Ophthalmic Imaging March 2024

Distinct Pathways of Macular Atrophy in Type 3 Macular Neovascularization Associated With AMD

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Enrico Borrelli; Costanza Barresi; Federico Ricardi; Alessandro Berni; Domenico Grosso; Pasquale Viggiano; Paola Marolo; Ugo Introini; Michele Reibaldi; Francesco Bandello
TAGS: atrophoderma maculatum, macular neovascularization, type 3 macular neovascularization, eye
Invest. Ophthalmol. Vis. Sci.. 2024; 65(3):18. https://doi.org/10.1167/iovs.65.3.18

Multidisciplinary Ophthalmic Imaging March 2024

Quantitative Evaluation of the Topographical Maps of Three-Dimensional Choroidal Vascularity Index in Children With Different Degrees of Myopia

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Fang Liu; Yuhao Ye; Weiming Yang; Jing Wang; Ye Xu; Yu Zhao; Meng Li; Zhi Chen; Yang Shen; Meiyan Li; Xingtao Zhou
TAGS: cardiovascular imaging, child, cortical blindness, maps, myopia
Invest. Ophthalmol. Vis. Sci.. 2024; 65(3):14. https://doi.org/10.1167/iovs.65.3.14

Includes: Supplemental Content

Visual Psychophysics and Physiological Optics February 2024

Spectral Dependence of Light Exposure on Retinal Pigment Epithelium Disruption in Living Primate Retina

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Jie Zhang; Ranjani Sabarinathan; Tracy Bubel; Wuao Jia; David R. Williams; Jennifer J. Hunter
TAGS: light exposure, primates, retina, retinal pigment epithelium, social reciprocity, wavelength, eye, photoreceptors, action spectrum, diagnostic imaging
Invest. Ophthalmol. Vis. Sci.. 2024; 65(2):43. https://doi.org/10.1167/iovs.65.2.43

Includes: Supplemental Content

Review February 2024

Deep Learning and Machine Learning Algorithms for Retinal Image Analysis in Neurodegenerative Disease: Systematic Review of Datasets and Models

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Tyler Bahr; Truong A. Vu; Jared J. Tuttle; Raymond Iezzi
TAGS: datasets, deep learning, neurodegenerative disorders, nerve degeneration, machine learning, systematic reviews
Trans. Vis. Sci. Tech.. 2024; 13(2):16. https://doi.org/10.1167/tvst.13.2.16

Includes: Supplemental Content

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology February 2024

In Vivo Imaging of Secondary Neurodegeneration Associated With Phosphatidylserine Externalization Along Axotomized Axons

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Fan Yang; Mohammadali Almasieh; Leonard A. Levin
TAGS: axon, axotomy, diagnostic imaging, nerve degeneration, phosphatidylserines, wounds and injuries, lasers, retrograde degeneration
Invest. Ophthalmol. Vis. Sci.. 2024; 65(2):24. https://doi.org/10.1167/iovs.65.2.24

Includes: Supplemental Content

Retina February 2024

A Novel Exploration of the Choroidal Vortex Vein System: Incidence and Characteristics of Posterior Vortex Veins in Healthy Eyes

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Guiqin He; Xiongze Zhang; Xuenan Zhuang; Yunkao Zeng; Yuhong Gan; Yongyue Su; Miaoling Li; Yuying Ji; Lan Mi; Xuelin Chen; Feng Wen
TAGS: eye, incidence
Invest. Ophthalmol. Vis. Sci.. 2024; 65(2):21. https://doi.org/10.1167/iovs.65.2.21

Includes: Supplemental Content

Retina February 2024

Deep Learning Detection of Early Retinal Peripheral Degeneration From Ultra-Widefield Fundus Photographs of Asymptomatic Young Adult (17–19 Years) Candidates to Airforce Cadets

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Tengyun Wu; Lie Ju; Xuefei Fu; Bin Wang; Zongyuan Ge; Yong Liu
TAGS: deep learning, fundus photography, tissue degeneration, young adult, optic disk, macula lutea, screening, training
Trans. Vis. Sci. Tech.. 2024; 13(2):1. https://doi.org/10.1167/tvst.13.2.1

Includes: Supplemental Content

Retina January 2024

Choriocapillaris and Retinal Vascular Alterations in Presymptomatic Alzheimer's Disease

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Giulia Corradetti; Deniz Oncel; Shin Kadomoto; Xianghong Arakaki; Robert A. Kloner; Alfredo A. Sadun; SriniVas R. Sadda; Jane W. Chan
TAGS: alzheimer's disease, chief complaint, tau proteins, face, biological markers
Invest. Ophthalmol. Vis. Sci.. 2024; 65(1):47. https://doi.org/10.1167/iovs.65.1.47

Retina January 2024

Fluorescence Lifetime Imaging Ophthalmoscopy of Mouse Models of Age-related Macular Degeneration

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Svenja Rebecca Sonntag; Britta Klein; Ralf Brinkmann; Salvatore Grisanti; Yoko Miura
TAGS: age-related macular degeneration, apolipoprotein e, diagnostic imaging, fluorescence, mice, ophthalmoscopy, total arterial compliance, trigeminal autonomic cephalalgias, teller acuity cards, lipids
Trans. Vis. Sci. Tech.. 2024; 13(1):24. https://doi.org/10.1167/tvst.13.1.24

Includes: Supplemental Content

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Real-Time Temperature-Controlled Retinal Laser Irradiation in Rabbits

Fluorescence Lifetime Imaging of Human Retinal Pigment Epithelium in Pentosan Polysulfate Toxicity Using Adaptive Optics Scanning Light Ophthalmoscopy

Retinal Fractal Dimension Is a Potential Biomarker for Systemic Health—Evidence From a Mixed-Age, Primary-Care Population

Short-Term Myopic Defocus and Choroidal Thickness in Children and Adults

Early Single-Examination Optical Coherence Tomography Biomarkers for Treatment-Requiring Retinopathy of Prematurity

Early Choriocapillaris Loss in a Porcine Model of RPE Cell Debridement Precedes Pathology That Simulates Advanced Macular Degeneration

Deep Learning-Based Automated Detection of Retinal Breaks and Detachments on Fundus Photography

OCTA Signal Quality Augmentation Using the Isometric Handgrip Test to Maximize Vascular Flow (SQUEEZE): A Randomized Crossover Trial

Adaptive Optics Retinal Imaging in RDH12 -Associated Early Onset Severe Retinal Dystrophy

RobOCTNet: Robotics and Deep Learning for Referable Posterior Segment Pathology Detection in an Emergency Department Population

Acetazolamide Challenge Changes Outer Retina Bioenergy-Linked and Anatomical OCT Biomarkers Depending on Mouse Strain

Distinct Pathways of Macular Atrophy in Type 3 Macular Neovascularization Associated With AMD

Quantitative Evaluation of the Topographical Maps of Three-Dimensional Choroidal Vascularity Index in Children With Different Degrees of Myopia

Spectral Dependence of Light Exposure on Retinal Pigment Epithelium Disruption in Living Primate Retina

Deep Learning and Machine Learning Algorithms for Retinal Image Analysis in Neurodegenerative Disease: Systematic Review of Datasets and Models

In Vivo Imaging of Secondary Neurodegeneration Associated With Phosphatidylserine Externalization Along Axotomized Axons

A Novel Exploration of the Choroidal Vortex Vein System: Incidence and Characteristics of Posterior Vortex Veins in Healthy Eyes

Deep Learning Detection of Early Retinal Peripheral Degeneration From Ultra-Widefield Fundus Photographs of Asymptomatic Young Adult (17–19 Years) Candidates to Airforce Cadets

Choriocapillaris and Retinal Vascular Alterations in Presymptomatic Alzheimer's Disease

Fluorescence Lifetime Imaging Ophthalmoscopy of Mouse Models of Age-related Macular Degeneration

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