Clinical and Epidemiologic Research

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Retina December 2024

Patient-Reported Experience Measurements From Individuals With Inherited Retinal Disorders Involved in Observational Research

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Malena Daich Varela; Shaima Hashem; Dayyanah Sumodhee; Michel Michaelides
TAGS: observational studies, questionnaires, retinal diseases
Trans. Vis. Sci. Tech.. 2024; 13(12):9. https://doi.org/10.1167/tvst.13.12.9

Includes: Supplemental Content

Clinical and Epidemiologic Research December 2024

Natural Course of Refractive Error in Congenital Stationary Night Blindness: Implications for Myopia Treatment

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Mariëlle M. F. Poels; Gerard C. de Wit; Mieke M. C. Bijveld; Maria M. van Genderen
TAGS: myopia, night blindness, congenital stationary, refraction, refractive errors
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):9. https://doi.org/10.1167/iovs.65.14.9

Includes: Supplemental Content

Clinical and Epidemiologic Research December 2024

Change in Systemic Medication and its Influence on Intraocular Pressure – Results From the Gutenberg Health Study

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Panagiotis Laspas; Alica Hartmann; Ida Scholz; Esther Maria Hoffmann; Anthony P. Khawaja; Karl Johannes Lackner; Thomas Münzel; Jasmin Ghaemi Kerahrodi; Irene Schmidtmann; Oliver Tüscher; Jörn Markus Schattenberg; Norbert Pfeiffer; Stavros Konstantinides; Philipp Sebastian Wild; Alexander Karl-Georg Schuster
TAGS: intraocular pressure, pharmaceutical preparations, health, beta-blockers
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):4. https://doi.org/10.1167/iovs.65.14.4

Includes: Supplemental Content

Clinical and Epidemiologic Research November 2024

Ranked Importance of Visual Function Outcome Measures in Choroideremia Clinical Trials

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Amandeep Singh Josan; Laura Jayne Taylor; Kanmin Xue; Jasmina Cehajic-Kapetanovic; Robert Edward MacLaren
TAGS: choroideremia, functional measures, outcome measures, vision
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):58. https://doi.org/10.1167/iovs.65.13.58

Includes: Supplemental Content

Retina November 2024

Influencing Factors on Pupillary Light Responses as a Biomarker for Local Retinal Function in a Large Normative Cohort

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Ricarda Jendritza; Krunoslav Stingl; Torsten Strasser; Ronja Jung; Felix Tonagel; Paul Richter; Anton Sonntag; Tobias Peters; Helmut Wilhelm; Barbara Wilhelm; Carina Kelbsch
TAGS: biological markers, cardiac progenitor cells, cohort studies, pupil, pupil light reflex, retinal cone, rod photoreceptors
Invest. Ophthalmol. Vis. Sci.. 2024; 65(6):3. https://doi.org/10.1167/iovs.65.6.3

Clinical and Epidemiologic Research November 2024

Adult Myopia Progression

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Noel A. Brennan; Xu Cheng; Mark A. Bullimore
TAGS: adult, myopia, refractive errors
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):49. https://doi.org/10.1167/iovs.65.13.49

Includes: Supplemental Content

Clinical and Epidemiologic Research November 2024

The Impact of HLA-A29 Homozygosity and of the Second HLA-A Allele on Susceptibility and Severity of Birdshot Chorioretinitis

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Jordan Loeliger; Romain Lhotte; Sahar Gelfman; Eli A. Stahl; Dominique Monnet; Valentin Clichet; Linda Imikirene; Souhila Kecili; Jean-Luc Taupin; Thierry Tabary; Jacques H. M. Cohen; Antoine P. Brézin
TAGS: alleles, disease susceptibility, hla-a antigens, homozygote, human leukocyte antigens, vitiliginous chorioretinitis
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):47. https://doi.org/10.1167/iovs.65.13.47

Includes: Supplemental Content

Clinical and Epidemiologic Research November 2024

Impact of Astigmatism on Axial Elongation in School-Age Children: A Five-Year Population-Based Study in Tianjin, China

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Dong Liang; Bei Du; Tsz-Wing Leung; Zhuzhu Liu; Qiang Su; Nan Jin; Ziyu Zhang; Mingguang He; Hua Yan; Ruihua Wei; Chea-Su Kee
TAGS: astigmatism, refractive errors
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):45. https://doi.org/10.1167/iovs.65.13.45

Includes: Supplemental Content

Genetics November 2024

Oxidative Stress and Inflammation-Related mRNAs Are Elevated in Serum of a Finnish Wet AMD Cohort

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Mikko Liukkonen; Hanna Heloterä; Leea Siintamo; Bishwa Ghimire; Pirkko Mattila; Niko Kivinen; Joanna Kostanek; Cezary Watala; Maria Hytti; Juha Hyttinen; Ali Koskela; Janusz Blasiak; Kai Kaarniranta
TAGS: cohort studies, finnish, genes, inflammation, oxidative stress, rna, rna, messenger
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):30. https://doi.org/10.1167/iovs.65.13.30

Includes: Supplemental Content

Retina November 2024

Potential Drug Targets for Diabetic Retinopathy Identified Through Mendelian Randomization Analysis

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Huan Liu; Feiyan Wang; Ziqing Hu; Jing Wei
TAGS: diabetic retinopathy, drug delivery systems, mendelian randomization analysis, plasma proteins, proteins
Trans. Vis. Sci. Tech.. 2024; 13(11):17. https://doi.org/10.1167/tvst.13.11.17

Includes: Supplemental Content

Clinical and Epidemiologic Research November 2024

Potential Prognostic Protein Biomarkers in Tears From Noninfectious Uveitis Patients Under Biologic Treatment as a Prelude to Personalized Medicine

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Lorena Rodríguez-Martínez; Carmen Antía Rodríguez-Fernández; Olalla Rodríguez Lemos; Begoña de Domingo; Pere García Bru; Jesús Mateos; Anxo Fernández-Ferreiro
TAGS: biological markers, proteins, tumor necrosis factors, uveitis, individualized medicine, patient prognosis
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):29. https://doi.org/10.1167/iovs.65.13.29

Includes: Supplemental Content

Genetics November 2024

Investigating Microperimetric Features in Bietti Crystalline Dystrophy Patients: A Cross-Sectional Longitudinal Study in a Large Cohort

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Yufei Xu; Xiao Liu; Nan Wu; Yanling Long; Jiayun Ren; Yu Wang; Xinyi Su; Zengping Liu; Yu Fujinami-Yokokawa; Kaoru Fujinami; Fang Chen; Xiaohong Meng; Yong Liu
TAGS: cohort studies, crystal structure, disease progression, eye, fovea centralis, longitudinal studies, genotype, vision, blindness, mutation
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):27. https://doi.org/10.1167/iovs.65.13.27

Includes: Supplemental Content

Clinical and Epidemiologic Research November 2024

Exploring the Relationship Between Refractive Errors and Common Chronic Diseases Via Blood Biochemistry Tests: A Large Prospective Cohort Study

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Yanze Yu; Hao Chen; Zhanying Wang; Yuhao Ye; Zhe Zhang; Yongle Bao; Yingnan Jia; Xingtao Zhou; Jing Zhao
TAGS: biochemistry, chronic disease, diabetes mellitus, type 2, myopia, prospective studies, refractive errors
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):26. https://doi.org/10.1167/iovs.65.13.26

Includes: Supplemental Content

Retina November 2024

Seasonal Variation in ATP-Induced Retinal Damage in the Cone-Dominant 13-Lined Ground Squirrel

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Owen R. Bowie; Hannah M. Follett; Ching Tzu Yu; Chloe Guillaume; Phyllis M. Summerfelt; Nicole Manfredonia; Jenna Grieshop; Dana K. Merriman; Sergey Tarima; Joseph Carroll
TAGS: cohort studies, diagnostic imaging, follow-up, intravitreal injections, retinal cone, scanning laser ophthalmoscopy, seasonal variation, mosaicism, injections, mosaic trial
Trans. Vis. Sci. Tech.. 2024; 13(11):5. https://doi.org/10.1167/tvst.13.11.5

Includes: Supplemental Content

Clinical and Epidemiologic Research October 2024

Association of Ambient Air Pollution Exposure With Incident Glaucoma: 12-Year Evidence From the UK Biobank Cohort

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Zihan Sun; Kelsey V. Stuart; Robert N. Luben; Amy L. Auld; Nicholas G. Strouthidis; Peng T. Khaw; Hari Jayaram; Anthony P. Khawaja; Paul J. Foster; on behalf of the UK Biobank Eye and Vision Consortium
TAGS: air pollution, cohort studies, glaucoma, uk biobank
Invest. Ophthalmol. Vis. Sci.. 2024; 65(12):22. https://doi.org/10.1167/iovs.65.12.22

Includes: Supplemental Content

Clinical and Epidemiologic Research October 2024

Glial Cell Responses and Gene Expression Dynamics in Retinas of Treated and Untreated RPE65 Mutant Dogs

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Tatyana Appelbaum; Evelyn Santana; David A. Smith; William A. Beltran; Gustavo D. Aguirre
TAGS: did not receive therapy or drug, dog, domestic, retina, rpe65 protein, neuroglia, gene expression, middle-aged adult
Invest. Ophthalmol. Vis. Sci.. 2024; 65(12):18. https://doi.org/10.1167/iovs.65.12.18

Includes: Supplemental Content

Retina October 2024

Effect of Ocular Perfusion Pressure on Incidence of Diabetic Retinopathy in Type 2 Diabetes: A Two-Year Prospective Study

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Yayi Yan; Xinyan Wu; Yuntong Li; Yiran Fan; Lingyi Li; Ching-Kit Tsui; Kaiqun Liu; Wenyong Huang; Xiaoling Liang; Andina Hu; on behalf of GDES Group
TAGS: diabetes mellitus, type 2, diabetic retinopathy, incidence, mopp protocol, perfusion, prospective studies
Trans. Vis. Sci. Tech.. 2024; 13(10):20. https://doi.org/10.1167/tvst.13.10.20

Multidisciplinary Ophthalmic Imaging October 2024

Severity Stratification of Coronary Artery Disease Using Novel Inner Ellipse-Based Foveal Avascular Zone Biomarkers

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Natasa Jeremic; Maximilian Pawloff; Dmitrii Lachinov; Stephanie Rokitansky; Matthias Hasun; Franz Weidinger; Andreas Pollreisz; Hrvoje Bogunović; Ursula Schmidt-Erfurth
TAGS: biological markers, coronary arteriosclerosis, stratification
Invest. Ophthalmol. Vis. Sci.. 2024; 65(12):15. https://doi.org/10.1167/iovs.65.12.15

Includes: Supplemental Content

Visual Psychophysics and Physiological Optics October 2024

Statistical Model of Ocular Wavefronts With Accommodation

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María Mechó-García; María Arcas-Carbonell; Elvira Orduna-Hospital; Ana Sánchez-Cano; Norberto López-Gil; Rute J. Macedo-de-Araújo; Miguel Faria-Ribeiro; Paulo Fernandes; José Manuel González-Méijome; Jos Rozema
TAGS: models, statistical, visual accommodation
Invest. Ophthalmol. Vis. Sci.. 2024; 65(12):12. https://doi.org/10.1167/iovs.65.12.12

Includes: Supplemental Content

Clinical and Epidemiologic Research October 2024

Initial Retinal Nerve Fiber Layer Loss and Risk of Diabetic Retinopathy Over a Four-Year Period

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Xiaoying Zhong; Huangdong Li; Shaoying Tan; Shaopeng Yang; Ziyu Zhu; Wenyong Huang; Weijing Cheng; Wei Wang
TAGS: diabetes mellitus, diabetes mellitus, type 2, diabetic retinopathy, retinal nerve fiber layer, follow-up, predictive value
Invest. Ophthalmol. Vis. Sci.. 2024; 65(12):5. https://doi.org/10.1167/iovs.65.12.5

Includes: Supplemental Content

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Patient-Reported Experience Measurements From Individuals With Inherited Retinal Disorders Involved in Observational Research

Natural Course of Refractive Error in Congenital Stationary Night Blindness: Implications for Myopia Treatment

Change in Systemic Medication and its Influence on Intraocular Pressure – Results From the Gutenberg Health Study

Ranked Importance of Visual Function Outcome Measures in Choroideremia Clinical Trials

Influencing Factors on Pupillary Light Responses as a Biomarker for Local Retinal Function in a Large Normative Cohort

Adult Myopia Progression

The Impact of HLA-A29 Homozygosity and of the Second HLA-A Allele on Susceptibility and Severity of Birdshot Chorioretinitis

Impact of Astigmatism on Axial Elongation in School-Age Children: A Five-Year Population-Based Study in Tianjin, China

Oxidative Stress and Inflammation-Related mRNAs Are Elevated in Serum of a Finnish Wet AMD Cohort

Potential Drug Targets for Diabetic Retinopathy Identified Through Mendelian Randomization Analysis

Potential Prognostic Protein Biomarkers in Tears From Noninfectious Uveitis Patients Under Biologic Treatment as a Prelude to Personalized Medicine

Investigating Microperimetric Features in Bietti Crystalline Dystrophy Patients: A Cross-Sectional Longitudinal Study in a Large Cohort

Exploring the Relationship Between Refractive Errors and Common Chronic Diseases Via Blood Biochemistry Tests: A Large Prospective Cohort Study

Seasonal Variation in ATP-Induced Retinal Damage in the Cone-Dominant 13-Lined Ground Squirrel

Association of Ambient Air Pollution Exposure With Incident Glaucoma: 12-Year Evidence From the UK Biobank Cohort

Glial Cell Responses and Gene Expression Dynamics in Retinas of Treated and Untreated RPE65 Mutant Dogs

Effect of Ocular Perfusion Pressure on Incidence of Diabetic Retinopathy in Type 2 Diabetes: A Two-Year Prospective Study

Severity Stratification of Coronary Artery Disease Using Novel Inner Ellipse-Based Foveal Avascular Zone Biomarkers

Statistical Model of Ocular Wavefronts With Accommodation

Initial Retinal Nerve Fiber Layer Loss and Risk of Diabetic Retinopathy Over a Four-Year Period

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