Cornea

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Cornea & External Disease September 2024

Causal Association Between Atopic Dermatitis and Keratoconus: A Mendelian Randomization Study

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Yuan Chang; Tianze Huang; Shan Yang; Ying Li; Di Chen
TAGS: atopic dermatitis, keratoconus, mendelian randomization analysis, genome-wide association study, datasets
Trans. Vis. Sci. Tech.. 2024; 13(9):13. https://doi.org/10.1167/tvst.13.9.13

Includes: Supplemental Content

Cornea September 2024

RNA-Seq Analysis Unraveling Novel Genes and Pathways Influencing Corneal Wound Healing

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Rajnish Kumar; Ratnakar Tripathi; Nishant R. Sinha; Rajiv R. Mohan
TAGS: cornea, genes, rna-seq, wound healing, proteins, rna, polymerase chain reaction, myofibroblasts
Invest. Ophthalmol. Vis. Sci.. 2024; 65(11):13. https://doi.org/10.1167/iovs.65.11.13

Includes: Supplemental Content

Artificial Intelligence September 2024

Eye-Rubbing Detection Using a Smartwatch: A Feasibility Study Demonstrated High Accuracy With Machine Learning

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Sina Elahi; Tom Mery; Christophe Panthier; Alain Saad; Damien Gatinel; Alexandre Alahi
TAGS: attention, datasets, eye, feasibility studies, machine learning, sensor, smartwatches, face, training
Trans. Vis. Sci. Tech.. 2024; 13(9):1. https://doi.org/10.1167/tvst.13.9.1

Cornea August 2024

The Necroptosis Pathway Is Upregulated in the Cornea in Mice With Ocular Graft-Versus-Host Disease

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Kazuki Asai; Hyung Keun Lee; Shinri Sato; Eisuke Shimizu; Jaehun Jung; Takahiro Okazaki; Mamoru Ogawa; Shigeto Shimmura; Kazuo Tsubota; Yoko Ogawa; Kazuno Negishi; Masatoshi Hirayama
TAGS: cornea, graft-versus-host disease, mice, necroptosis, proteins, up-regulation (physiology)
Invest. Ophthalmol. Vis. Sci.. 2024; 65(10):38. https://doi.org/10.1167/iovs.65.10.38

Includes: Supplemental Content

Genetics August 2024

Gene‒Environment Interaction Between CAST Gene and Eye-Rubbing in the Chinese Keratoconus Cohort Study: A Case-Only Study

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Shanshan Yin; Liyan Xu; Kaili Yang; Qi Fan; Yuwei Gu; Chenchen Yin; Yonghao Zang; Yifan Wang; Yi Yuan; Anqi Chang; Chenjiu Pang; Shengwei Ren
TAGS: chinese (other dialects), cohort studies, eye, genes, keratoconus, chinese people, gene-environment interaction
Invest. Ophthalmol. Vis. Sci.. 2024; 65(10):36. https://doi.org/10.1167/iovs.65.10.36

Artificial Intelligence August 2024

Automatic Determination of Endothelial Cell Density From Donor Cornea Endothelial Cell Images

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Beth Ann M. Benetz; Ved S. Shivade; Naomi M. Joseph; Nathan J. Romig; John C. McCormick; Jiawei Chen; Michael S. Titus; Onkar B. Sawant; Jameson M. Clover; Nathan Yoganathan; Harry J. Menegay; Robert C. O'Brien; David L. Wilson; Jonathan H. Lass
TAGS: cornea, deep learning, donors, endothelial cells, scleroderma, coup de sabre, eye banks, training
Trans. Vis. Sci. Tech.. 2024; 13(8):40. https://doi.org/10.1167/tvst.13.8.40

Includes: Supplemental Content

Cornea & External Disease August 2024

Effect of Topical Losartan in the Treatment of Established Corneal Fibrosis in Rabbits

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Valeria Villabona Martinez; Barbara Araujo Lima Dutra; Marcony R. Santhiago; Steven E. Wilson
TAGS: cornea, fibrosis, losartan, oryctolagus cuniculus
Trans. Vis. Sci. Tech.. 2024; 13(8):22. https://doi.org/10.1167/tvst.13.8.22

Clinical and Epidemiologic Research August 2024

Localized Evaporative Cooling Explains Observed Ocular Surface-Temperature Patterns

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Young Hyun Kim; Joshua Lee; Sarah M. Yi; Meng C. Lin; Clayton J. Radke
TAGS: body temperature, cornea, evaporation, ocular surfaces, temperature, tear film finding
Invest. Ophthalmol. Vis. Sci.. 2024; 65(10):15. https://doi.org/10.1167/iovs.65.10.15

Includes: Supplemental Content

Cornea August 2024

Fabry Disease Rat Model Develops Age- and Sex-Dependent Anterior Segment Ocular Abnormalities

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Madelyn E. Erdman; Sanjay Ch; Amer Mohiuddin; Khalid Al-Kirwi; Molly R. Rasper; Sibabalo Sokupa; Shermaine W. Y. Low; Christine M. B. Skumatz; Vinicius De Stefano; Iris S. Kassem; Shyam S. Chaurasia
TAGS: eye abnormalities, fabry disease, genotype, rats, cornea, adult, cataract
Invest. Ophthalmol. Vis. Sci.. 2024; 65(10):14. https://doi.org/10.1167/iovs.65.10.14

Includes: Supplemental Content

Cornea August 2024

Ex Vivo Lenticule Customization for Stromal Lenticule Addition Keratoplasty

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Mario Nubile; Jorge L. Alio del Barrio; Luca Cerino; Niccolò Salgari; Mona El Zarif; Michele Totta; Manuela Lanzini; Leonardo Mastropasqua
TAGS: cornea, implantation procedure, keratoconus, keratoplasty, shape, retinal cone
Invest. Ophthalmol. Vis. Sci.. 2024; 65(10):9. https://doi.org/10.1167/iovs.65.10.9

Includes: Supplemental Content

Clinical Trials July 2024

Utility of a Model to Predict Endothelial Cell Density of Donor Corneas to Determine Suitability for Transplantation

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Julia B. Bu; Stephanie D. Grabitz; Franziska Schön; Melissa Apel; Tobias Pusch; Adrian Gericke; Alicia Poplawski; Norbert Pfeiffer; Joanna Wasielica-Poslednik
TAGS: cornea, donors, endothelial cells, transplantation
Trans. Vis. Sci. Tech.. 2024; 13(7):21. https://doi.org/10.1167/tvst.13.7.21

Includes: Supplemental Content

Cornea July 2024

High Resolution Images of Human Meibum Spread on Saline

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P. Ewen King-Smith; Carolyn G. Begley; Richard J. Braun
TAGS: lipids, saline solutions, pixel
Invest. Ophthalmol. Vis. Sci.. 2024; 65(8):41. https://doi.org/10.1167/iovs.65.8.41

Retina July 2024

Characterization of Ocular Morphology in Col4a3 −/− Mice as a Murine Model for Alport Syndrome

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Yuwei Wang; Ruilin Zhu; Liang Zhao; Fang Wang; Yanqin Zhang; Shiguang Liu; Jie Ding; Liu Yang
TAGS: mice, hereditary nephritis, collagen type iv, language morphology, morphology, lens capsule, crystalline
Trans. Vis. Sci. Tech.. 2024; 13(7):16. https://doi.org/10.1167/tvst.13.7.16

Includes: Supplemental Content

Article July 2024

Wide-field optical eye models for emmetropic and myopic eyes

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Gareth D. Hastings; Pavan Tiruveedhula; Austin Roorda
TAGS: eye, optics, visual accommodation
Journal of Vision. 2024; 24(7):9. https://doi.org/10.1167/jov.24.7.9

Includes: Supplemental Content

Review July 2024

Photoactivated Chromophore for Keratitis-Corneal Cross-linking (PACK-CXL)—A Scoping Review Based on Preclinical Studies

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Malwina E. Kowalska; Simon A. Pot; Sonja Hartnack
TAGS: corneal collagen cross-linking, keratitis, chromophore, cross-linking, surrogate endpoints, cornea, pre-clinical research
Trans. Vis. Sci. Tech.. 2024; 13(7):14. https://doi.org/10.1167/tvst.13.7.14

Includes: Supplemental Content

Immunology and Microbiology July 2024

Inhibition of Cathepsin S in Autoimmune CD25KO Mouse Improves Sjögren Disease–Like Lacrimal Gland Pathology

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Kaitlin K. Scholand; Jeremias Galletti; Wolfgang Haap; Tiago Santos-Ferreira; Christoph Ullmer; Cintia S. de Paiva
TAGS: autoimmunity, cathepsins, mice, sjogren's syndrome, pathology, t-lymphocytes, lacrimal gland, cornea
Invest. Ophthalmol. Vis. Sci.. 2024; 65(8):26. https://doi.org/10.1167/iovs.65.8.26

Includes: Supplemental Content

Cornea July 2024

Reticulated Retinoic Acid Synthesis is Implicated in the Pathogenesis of Dry Eye in Aqp5 Deficiency Mice

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Huanhuan Ge; Guohu Di; Bin Li; Wenshuo Han; Peirong Song; Shiheng Han; Dianqiang Wang; Peng Chen
TAGS: chronic exertional compartment syndrome, cornea, dry eye syndromes, mice, pathogenesis, polymerase chain reaction, sodium chloride, tretinoin, transcription factor, corneal epithelium
Invest. Ophthalmol. Vis. Sci.. 2024; 65(8):25. https://doi.org/10.1167/iovs.65.8.25

Includes: Supplemental Content

Cornea & External Disease July 2024

Tear Fluid Progranulin as a Noninvasive Biomarker for the Monitoring of Corneal Innervation Changes in Patients With Type 2 Diabetes Mellitus

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Tianyi Zhou; Zhiwei Dou; Yuchen Cai; Dongqing Zhu; Yao Fu
TAGS: biological markers, cornea, diabetes mellitus, diabetes mellitus, type 2, grn gene, nerve supply, neurons, progranulins, dry eye syndromes
Trans. Vis. Sci. Tech.. 2024; 13(7):9. https://doi.org/10.1167/tvst.13.7.9

Cornea July 2024

The Role of LC3-Associated Phagocytosis Inhibits the Inflammatory Response in Aspergillus fumigatus Keratitis

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Junjie Luan; Ziyue Zhang; Qian Wang; Cui Li; Hao Zhang; Yingxue Zhang; Xudong Peng; Guiqiu Zhao; Jing Lin
TAGS: cornea, immune response, keratitis, mice, phagocytosis, inflammatory response, aspergillus fumigatus, proteins, clec7a gene
Invest. Ophthalmol. Vis. Sci.. 2024; 65(8):4. https://doi.org/10.1167/iovs.65.8.4

Cornea July 2024

Physiological Effects of Soat1 Inactivation on Homeostasis of the Mouse Ocular Surface

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Amber Wilkerson; Seher Yuksel; Riya Acharya; Igor A. Butovich
TAGS: cornea, mice, ocular surfaces
Invest. Ophthalmol. Vis. Sci.. 2024; 65(8):2. https://doi.org/10.1167/iovs.65.8.2

Includes: Supplemental Content

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Causal Association Between Atopic Dermatitis and Keratoconus: A Mendelian Randomization Study

RNA-Seq Analysis Unraveling Novel Genes and Pathways Influencing Corneal Wound Healing

Eye-Rubbing Detection Using a Smartwatch: A Feasibility Study Demonstrated High Accuracy With Machine Learning

The Necroptosis Pathway Is Upregulated in the Cornea in Mice With Ocular Graft-Versus-Host Disease

Gene‒Environment Interaction Between CAST Gene and Eye-Rubbing in the Chinese Keratoconus Cohort Study: A Case-Only Study

Automatic Determination of Endothelial Cell Density From Donor Cornea Endothelial Cell Images

Effect of Topical Losartan in the Treatment of Established Corneal Fibrosis in Rabbits

Localized Evaporative Cooling Explains Observed Ocular Surface-Temperature Patterns

Fabry Disease Rat Model Develops Age- and Sex-Dependent Anterior Segment Ocular Abnormalities

Ex Vivo Lenticule Customization for Stromal Lenticule Addition Keratoplasty

Utility of a Model to Predict Endothelial Cell Density of Donor Corneas to Determine Suitability for Transplantation

High Resolution Images of Human Meibum Spread on Saline

Characterization of Ocular Morphology in Col4a3 −/− Mice as a Murine Model for Alport Syndrome

Wide-field optical eye models for emmetropic and myopic eyes

Photoactivated Chromophore for Keratitis-Corneal Cross-linking (PACK-CXL)—A Scoping Review Based on Preclinical Studies

Inhibition of Cathepsin S in Autoimmune CD25KO Mouse Improves Sjögren Disease–Like Lacrimal Gland Pathology

Reticulated Retinoic Acid Synthesis is Implicated in the Pathogenesis of Dry Eye in Aqp5 Deficiency Mice

Tear Fluid Progranulin as a Noninvasive Biomarker for the Monitoring of Corneal Innervation Changes in Patients With Type 2 Diabetes Mellitus

The Role of LC3-Associated Phagocytosis Inhibits the Inflammatory Response in Aspergillus fumigatus Keratitis

Physiological Effects of Soat1 Inactivation on Homeostasis of the Mouse Ocular Surface

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