Imaging

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Artificial Intelligence December 2024

A Deep Learning Network for Accurate Retinal Multidisease Diagnosis Using Multiview Fusion of En Face and B-Scan Images: A Multicenter Study

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Chubin Ou; Xifei Wei; Lin An; Jia Qin; Min Zhu; Mei Jin; Xiangbin Kong
TAGS: deep learning, face, multicenter studies
Trans. Vis. Sci. Tech.. 2024; 13(12):31. https://doi.org/10.1167/tvst.13.12.31

Includes: Supplemental Content

Cornea & External Disease December 2024

In Vivo Contactless, Cellular-Resolution Imaging of the Healthy and Pathological Human Limbus With 250-kHz Point-Scanning SD-OCT

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Kostadinka Bizheva; Zohreh Hosseinaee; Kirsten Carter; Denise Hileeto; Brian G. Ballios; Luigina Sorbara; Hall F. Chew
TAGS: body tissue, diagnostic imaging, spectral domain-optical coherence tomography, eye, cicatrix
Trans. Vis. Sci. Tech.. 2024; 13(12):29. https://doi.org/10.1167/tvst.13.12.29

Cornea & External Disease December 2024

Corneal Confocal Microscopy Identifies and Differentiates Patients With Multiple Sclerosis and Epilepsy

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Ioannis N. Petropoulos; Kareem Essam Aly; Shaikha Al-Thani; Georgios Ponirakis; Hoda Gad; Adnan Khan; Beatriz Canibano; Dirk Deleu; Naveed Akhtar; Gayane Melikyan; Boulenouar Mesraoua; Maria Siddiqi; Jon Perkins; Novsheen Mir; Reny Francis; Abdul Salam; Ahmed El-Sotouhy; Surjith Vattoth; Ahmed Own; Saadat Kamran; Rayaz A. Malik
TAGS: cornea, epilepsy, microscopy, confocal, multiple sclerosis, nerve degeneration
Trans. Vis. Sci. Tech.. 2024; 13(12):22. https://doi.org/10.1167/tvst.13.12.22

Retina December 2024

Band Visibility in High-Resolution Optical Coherence Tomography Assessed With a Custom Review Tool and Updated, Histology-Derived Nomenclature

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Lukas Goerdt; Thomas A. Swain; Deepayan Kar; Gerald McGwin; Andreas Berlin; Mark E. Clark; Cynthia Owsley; Kenneth R. Sloan; Christine A. Curcio
TAGS: eye, histology, optical coherence tomography, retina, software, reliability, volume electron microscopy, diagnostic imaging
Trans. Vis. Sci. Tech.. 2024; 13(12):19. https://doi.org/10.1167/tvst.13.12.19

Includes: Multimedia, Supplemental Content

Clinical Trials December 2024

A New Approach to Retinal Oxygen Extraction Measurement Based on Laser Speckle Flowgraphy and Retinal Oximetry

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Viktoria Pai; Patrick Janku; Theresa Lindner; Ulrich Graf; Leopold Schmetterer; Gerhard Garhöfer; Doreen Schmidl
TAGS: lasers, oximetry, oxygen, oxygen extraction, oxygen saturation measurement, vascular flow, hypoxia, inspiration, respiration, hyperoxia
Trans. Vis. Sci. Tech.. 2024; 13(12):12. https://doi.org/10.1167/tvst.13.12.12

Biochemistry and Molecular Biology December 2024

Sphingolipid Levels and Processing of the Retinyl Chromophore in the Retina of a Mouse Model of Niemann-Pick Disease

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Bushra Rahman; David M. G. Anderson; Chunhe Chen; Jian Liu; Lukasz G. Migas; Raf Van de Plas; Kevin L. Schey; Masahiro Kono; Jie Fan; Yiannis Koutalos
TAGS: chromophore, mice, niemann-pick diseases, retina, sphingolipids, vitamin a, spectrometry, mass, matrix-assisted laser desorption-ionization, sphingomyelins, diagnostic imaging, rod photoreceptors
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):24. https://doi.org/10.1167/iovs.65.14.24

Retina December 2024

Retinal Neurovascular Impairment in Full-Course Diabetic Retinopathy: The Guangdong Diabetic Retinopathy Multiple-Omics Study

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Chunran Lai; Ting Su; Jiahui Cao; Qinyi Li; Zijing Du; Yaxin Wang; Shan Wang; Qiaowei Wu; Yijun Hu; Ying Fang; Huiyi Liao; Zhuoting Zhu; Xianwen Shang; Mingguang He; Honghua Yu; Xiayin Zhang
TAGS: diabetes mellitus, type 2, diabetic retinopathy, electroretinography, nonproliferative diabetic retinopathy, peripheral neurovascular compromise, photopsia, retinal cone, optical coherence tomography, retina, photoreceptors
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):20. https://doi.org/10.1167/iovs.65.14.20

Includes: Supplemental Content

Retina December 2024

Onset and Progression of Disease in Nonhuman Primates With PDE6C Cone Disorder

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Monica Ardon; Lily Nguyen; Rui Chen; Jeffrey Rogers; Tim Stout; Sara Thomasy; Ala Moshiri
TAGS: disease progression, electroretinography, homozygote, infant, mutation, primates, retinal cone, macaca, adult, heterozygote
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):16. https://doi.org/10.1167/iovs.65.14.16

Includes: Supplemental Content

Retina December 2024

A Novel Grid Strategy for Correlating Focal Macular Anatomic Changes With Focal Changes in Choriocapillaris Perfusion

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Farhan E. Hiya; Yuxuan Cheng; Mengxi Shen; Jianqing Li; Alessandro Berni; Sandy Wenting Zhou; Gissel Herrera; Robert C. O'Brien; Giovanni Gregori; Ruikang K. Wang; Philip J. Rosenfeld
TAGS: chief complaint, drusen, eye, perfusion, reliability, diagnostic imaging, coronary arteriosclerosis, masks, computer assisted diagnosis, computer-aided detection systems
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):5. https://doi.org/10.1167/iovs.65.14.5

Retina December 2024

Characterization of the Retinal Circulation of the Mouse

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Fei Shang,; Jesse Schallek
TAGS: mice, retina circulation, vasculature, diagnostic imaging
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):3. https://doi.org/10.1167/iovs.65.14.3

Includes: Multimedia, Supplemental Content

Retina December 2024

The Umbra and the Penumbra: Longitudinal Effects of Geographic Atrophy in AMD on the Outer Choroid by Imaging Analysis and Histopathological Correlation

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Enrico Borrelli; Francesco Cappellani; Jose S. Pulido; Daniel Pauleikhoff; Imran A. Bhutto; D. Scott McLeod; Michele Reibaldi; Malia M. Edwards
TAGS: age-related macular degeneration, nonexudative, choroid, diagnostic imaging, eye, follow-up, histopathology tests, retinal pigment epithelium atrophy, chief complaint
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):2. https://doi.org/10.1167/iovs.65.14.2

Article November 2024

The choices hidden in photography

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Aaron Hertzmann
TAGS: photography, color, perception
Journal of Vision. 2024; 22(11):10. https://doi.org/10.1167/jov.22.11.10

Retina November 2024

Automated Detection of Drusenoid Pigment Epithelial Detachments From Spectral-Domain Optical Coherence Tomography in Patients With AMD

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Souvick Mukherjee; Cameron Duic; Tharindu De Silva; Tiarnan D. L. Keenan; Alisa T. Thavikulwat; Emily Y. Chew; Catherine Cukras
TAGS: drusen, retinal pigment epithelial detachment, spectral domain-optical coherence tomography, reading (activity), eye
Trans. Vis. Sci. Tech.. 2024; 13(11):25. https://doi.org/10.1167/tvst.13.11.25

Includes: Supplemental Content

Lens November 2024

Quantitative and Rapid In Vivo Imaging of Human Lenticular Fluorescence

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Joshua M. Herzog; Angela Verkade; Volker Sick
TAGS: diagnostic imaging, fluorescence, lens, crystalline, lens (device)
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):41. https://doi.org/10.1167/iovs.65.13.41

Retinal Cell Biology November 2024

Blind But Alive – Congenital Loss of atoh7 Disrupts the Visual System of Adult Zebrafish

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Juliane Hammer; Paul Röppenack; Sarah Yousuf; Anja Machate; Marika Fischer; Stefan Hans; Michael Brand
TAGS: adult, zebrafish, phenotype, visual system, retina
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):42. https://doi.org/10.1167/iovs.65.13.42

Includes: Supplemental Content

Retina November 2024

A High-Fidelity Computational Model for Predicting Blood Cell Trafficking and 3D Capillary Hemodynamics in Retinal Microvascular Networks

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Saman Ebrahimi; Phillip Bedggood; Yifu Ding; Andrew Metha; Prosenjit Bagchi
TAGS: blood capillaries, blood cells, computer simulation, fluid flow, hematocrit, hemodynamics, microcirculation, microvascular network, velocity, retail clinics
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):37. https://doi.org/10.1167/iovs.65.13.37

Includes: Multimedia, Supplemental Content

Multidisciplinary Ophthalmic Imaging November 2024

Evaluating the Impact of Retinal Vessel Segmentation Metrics on Retest Reliability in a Clinical Setting: A Comparative Analysis Using AutoMorph

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Samuel D. Giesser; Ferhat Turgut; Amr Saad; Jay R. Zoellin; Chiara Sommer; Yukun Zhou; Siegfried K. Wagner; Pearse A. Keane; Matthias Becker; Delia Cabrera DeBuc; Gábor Márk Somfai
TAGS: biological markers, image quality, reliability, retinal vessels
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):24. https://doi.org/10.1167/iovs.65.13.24

Includes: Supplemental Content

Retinal Cell Biology November 2024

Genetic and Cellular Basis of Impaired Phagocytosis and Photoreceptor Degeneration in CLN3 Disease

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Jimin Han; Sueanne Chear; Jana Talbot; Vicki Swier; Clarissa Booth; Cheyenne Reuben-Thomas; Sonal Dalvi; Jill M. Weimer; Alex W. Hewitt; Anthony L. Cook; Ruchira Singh
TAGS: autofluorescence, phagocytosis, photoreceptors, platypnea orthodeoxia syndrome, retinal pigment cell, tissue degeneration, genetics, lipofuscin, retina
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):23. https://doi.org/10.1167/iovs.65.13.23

Includes: Supplemental Content

Visual Neuroscience November 2024

The Electroretinogram I-Wave, a Component Originating in the Retinal OFF-Pathway, Associates With a Myopia Genetic Risk Polymorphism

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Zihe Xu; Jit Kai Tan; Krishnika Vetrivel; Xiaofan Jiang; Shaun M. Leo; Taha Bhatti; Ambreen Tariq; Andrew R. Webster; Anthony G. Robson; Christopher J. Hammond; Pirro G. Hysi; Omar A. Mahroo
TAGS: electroretinography, genetic risk, myopia, polymorphism
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):21. https://doi.org/10.1167/iovs.65.13.21

Includes: Supplemental Content

Retina November 2024

Factors Associated With Ocular Perfusion Measurements as Obtained With Laser Speckle Contrast Imaging

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Jacqueline Fröhlich; Marco Cattaneo; Philippe Valmaggia; Peter M. Maloca; Konstantin Gugleta; Leopold Schmetterer; Hendrik P.N. Scholl; Giacomo Calzetti
TAGS: laser speckle contrast imaging, optic disk, perfusion, vascular flow, eye, spectral domain-optical coherence tomography
Trans. Vis. Sci. Tech.. 2024; 13(11):8. https://doi.org/10.1167/tvst.13.11.8

Includes: Supplemental Content

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A Deep Learning Network for Accurate Retinal Multidisease Diagnosis Using Multiview Fusion of En Face and B-Scan Images: A Multicenter Study

In Vivo Contactless, Cellular-Resolution Imaging of the Healthy and Pathological Human Limbus With 250-kHz Point-Scanning SD-OCT

Corneal Confocal Microscopy Identifies and Differentiates Patients With Multiple Sclerosis and Epilepsy

Band Visibility in High-Resolution Optical Coherence Tomography Assessed With a Custom Review Tool and Updated, Histology-Derived Nomenclature

A New Approach to Retinal Oxygen Extraction Measurement Based on Laser Speckle Flowgraphy and Retinal Oximetry

Sphingolipid Levels and Processing of the Retinyl Chromophore in the Retina of a Mouse Model of Niemann-Pick Disease

Retinal Neurovascular Impairment in Full-Course Diabetic Retinopathy: The Guangdong Diabetic Retinopathy Multiple-Omics Study

Onset and Progression of Disease in Nonhuman Primates With PDE6C Cone Disorder

A Novel Grid Strategy for Correlating Focal Macular Anatomic Changes With Focal Changes in Choriocapillaris Perfusion

Characterization of the Retinal Circulation of the Mouse

The Umbra and the Penumbra: Longitudinal Effects of Geographic Atrophy in AMD on the Outer Choroid by Imaging Analysis and Histopathological Correlation

The choices hidden in photography

Automated Detection of Drusenoid Pigment Epithelial Detachments From Spectral-Domain Optical Coherence Tomography in Patients With AMD

Quantitative and Rapid In Vivo Imaging of Human Lenticular Fluorescence

Blind But Alive – Congenital Loss of atoh7 Disrupts the Visual System of Adult Zebrafish

A High-Fidelity Computational Model for Predicting Blood Cell Trafficking and 3D Capillary Hemodynamics in Retinal Microvascular Networks

Evaluating the Impact of Retinal Vessel Segmentation Metrics on Retest Reliability in a Clinical Setting: A Comparative Analysis Using AutoMorph

Genetic and Cellular Basis of Impaired Phagocytosis and Photoreceptor Degeneration in CLN3 Disease

The Electroretinogram I-Wave, a Component Originating in the Retinal OFF-Pathway, Associates With a Myopia Genetic Risk Polymorphism

Factors Associated With Ocular Perfusion Measurements as Obtained With Laser Speckle Contrast Imaging

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