Translational Research

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Retina March 2025

High-Performance, Low-Cost Optical Coherence Tomography System Using a Jetson Orin Nano for Real-Time Control and Image Processing

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Wan Wang; David A. Miller; Hillel B. Price; Xiangyue Yang; William J. Brown; Adam Wax
TAGS: optical coherence tomography, processing speed, software, benchmarking, diagnostic imaging
Trans. Vis. Sci. Tech.. 2025; 14(3):24. https://doi.org/10.1167/tvst.14.3.24

Cornea & External Disease March 2025

Comparing the Performance of Stress-Strain Index Versions 1 and 2 in Normal and Keratoconus Patients

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Nan-Ji Lu; Marta Jiménez-García; Ahmed Elsheikh; Ahmed Makarem; Carina Koppen; Jos J. Rozema
TAGS: keratoconus, stress, cornea, eye, tomography
Trans. Vis. Sci. Tech.. 2025; 14(3):23. https://doi.org/10.1167/tvst.14.3.23

Includes: Supplemental Content

Cornea & External Disease March 2025

Regional Biomechanical Weakening in Keratoconus Corneas Detected by In Vivo High-Frequency Ultrasound Elastography

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Sunny Kwok; Xueliang Pan; Manqi Pan; Zihao Chen; Madison Ammon; Andrew Hendershot; Jun Liu
TAGS: cornea, keratoconus, ultrasound elastography, ultrasonography, eye
Trans. Vis. Sci. Tech.. 2025; 14(3):22. https://doi.org/10.1167/tvst.14.3.22

Retina March 2025

Carboxyamidotriazole Complexed to PLGA Is Safe, Effective, and Durable in Models of Neovascular Retinal Disease

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Sergio Li Calzi; Ayaka Fujihashi; Dibyendu Chakraborty; Yvonne Adu-Rutledge; Ram Prasad; Edgar L. V. Ready; Sarbodeep Paul; Srikanth Kakumanu; Xiaoping Qi; Michael E. Boulton; Alan J. Franklin; Bob H. Katz; Maria B. Grant
TAGS: aflibercept, choroidal neovascularization, implants, lasers, oryctolagus cuniculus, polymers, retinal diseases, intravitreal injections, mice, injections
Trans. Vis. Sci. Tech.. 2025; 14(3):21. https://doi.org/10.1167/tvst.14.3.21

Retina March 2025

Evaluation of Suprachoroidal Injection in Cadaveric and Preclinical Models

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Mark Hedgeland; Sergio Camacho Gonzalez; Dimitrios Stampoulis; Vivian Lee; Kate Powell; Yubin Qiu; Robert Hodge; Greg Bell; Amanda Fago; Rebecca Atkinson-Dell; Nadya Choti; Kirsten Stoner
TAGS: injections, eye, subcutaneous injections
Trans. Vis. Sci. Tech.. 2025; 14(3):20. https://doi.org/10.1167/tvst.14.3.20

Includes: Multimedia, Supplemental Content

Artificial Intelligence March 2025

Corneal Layer Segmentation in Healthy and Pathological Eyes: A Joint Super-Resolution Generative Adversarial Network and Adaptive Graph Theory Approach

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Khin Yadanar Win; Jipson Wong Hon Fai; Wong Qiu Ying; Chloe Chua Si Qi; Jacqueline Chua; Damon Wong; Marcus Ang; Leopold Schmetterer; Bingyao Tan
TAGS: cornea, eye, generative adversarial networks, graphical displays
Trans. Vis. Sci. Tech.. 2025; 14(3):19. https://doi.org/10.1167/tvst.14.3.19

Cornea & External Disease March 2025

Enhanced Riboflavin Stromal Delivery Using Microchannel-Assisted Iontophoresis for Corneal Crosslinking

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Rohan Joshi; Samantha Bradford; Shangbang Luo; Emily Farrah; Yilu Xie; Donald J. Brown; Tibor Juhasz; James V. Jester
TAGS: corneal collagen cross-linking, iontophoresis, riboflavin, mass or substance concentration per volume, eye, oryctolagus cuniculus, cornea
Trans. Vis. Sci. Tech.. 2025; 14(3):18. https://doi.org/10.1167/tvst.14.3.18

Cornea & External Disease March 2025

Artificial Intelligence–Driven Detection of LASIK Using Corneal Optical Coherence Tomography Maps

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Jiachi Hong; Afshan A. Nanji; Richard D. Stutzman; Winston D. Chamberlain; Xubo Song; David Huang; Yan Li
TAGS: artificial intelligence, cornea, keratomileusis, laser in situ, maps, optical coherence tomography
Trans. Vis. Sci. Tech.. 2025; 14(3):17. https://doi.org/10.1167/tvst.14.3.17

Includes: Supplemental Content

Retina March 2025

Quantifying the Progression of Stargardt Disease in Double-Null ABCA4 Carriers Using Fundus Autofluorescence Imaging

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Ivana Mihalek; Hanna De Bruyn; Tomislav Glavan; Annie M. Lancos; Caitlin M. Ciolfi; Katarzyna Malendowicz; Sigrid Aslaksen; Laurie L. Molday; Robert S. Molday; Anne B. Fulton
TAGS: abca4 gene, fovea centralis, fundus autofluorescence imaging, pixel, stargardt's disease, artifacts, eye
Trans. Vis. Sci. Tech.. 2025; 14(3):16. https://doi.org/10.1167/tvst.14.3.16

Includes: Supplemental Content

Glaucoma March 2025

The Association of Social Determinants of Health on Monitoring for Disease Progression Among Patients With Primary Open-Angle Glaucoma

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Kunal Kanwar; Rithambara Ramachandran; Joshua D. Stein; Chris A. Andrews; Azraa S. Chaudhury; Maryam Ige; Xueqing Zhou; Shikha Marwah; Yang Li; Charlesnika T. Evans; Abel N. Kho; Paul J. Bryar; Dustin D. French; on behalf of the Sight Outcomes Research Collaborative (SOURCE) Consortium
TAGS: open-angle glaucoma, optic nerve, disease progression
Trans. Vis. Sci. Tech.. 2025; 14(3):15. https://doi.org/10.1167/tvst.14.3.15

Includes: Supplemental Content

Retina March 2025

The Combination of Retinal Neurovascular Unit Changes With Carotid Artery Stenosis Enhances the Prediction of Ischemic Stroke

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Zhifan Chen; Shuoxin Liao; Guangzhong Chen; Changmao Li; Chunling Liu; Junbin Liu; Guangyu Wu; Zheng Lyu; Mengya Liu; Xiyu Wu; Guixian Ma; Qianli Meng
TAGS: carotid stenosis, ischemic stroke
Trans. Vis. Sci. Tech.. 2025; 14(3):14. https://doi.org/10.1167/tvst.14.3.14

Includes: Supplemental Content

Artificial Intelligence March 2025

Retinal Microvascular Biomarker Assessment With Automated Algorithm and Semiautomated Software in the Montrachet Dataset

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Pétra Eid; Abderrahmane Bourredjem; Atif Anwer; Catherine Creuzot-Garcher; Pearse Andrew Keane; Yukun Zhou; Siegfried Wagner; Fabrice Meriaudeau; Louis Arnould
TAGS: biological markers, datasets, fundus photography, retinal imaging, software
Trans. Vis. Sci. Tech.. 2025; 14(3):13. https://doi.org/10.1167/tvst.14.3.13

Includes: Supplemental Content

Retina March 2025

Quantitative Evaluation of Changes in Retinal and Choroidal Blood Flow Following Strabismus Surgery

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Sayuri Yasuda; Yoshiko Takai; Yuma Yasuda; Takanori Yamamoto; Ryo Tomita; Takeshi Iwase; Norie Nonobe; Jun Takeuchi; Taiki Kojima; Koji M. Nishiguchi; Hiroki Kaneko
TAGS: strabismus, surgical procedures, operative, vascular flow
Trans. Vis. Sci. Tech.. 2025; 14(3):12. https://doi.org/10.1167/tvst.14.3.12

Glaucoma March 2025

Measurement of Aqueous Humor Viscosity in an Experimental Rabbit Model With Corneal Neovascularization

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Dong Eun Kim; Do Young Park; Jong Chul Han
TAGS: aqueous humor, corneal neovascularization, mass or substance concentration per volume, oryctolagus cuniculus, vascular endothelial growth factor a, viscosity, choroidal neovascularization, copy number polymorphism, eye, hypertension
Trans. Vis. Sci. Tech.. 2025; 14(3):9. https://doi.org/10.1167/tvst.14.3.9

Pediatric Ophthalmology & Strabismus March 2025

The Peripheral Defocus Designed Spectacle Lenses Might Increase Astigmatism in Myopic Children

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Wenyan Xu; Xiaoman Li; Jianing Zhang; Hongyi Li; Xuewen Ding; Xiaoyue Hu; Xinyue Quan; Yue Su; Fan Lu; Jie Chen
TAGS: astigmatism, child, lens (device), lens, crystalline, myopia, refractive errors
Trans. Vis. Sci. Tech.. 2025; 14(3):8. https://doi.org/10.1167/tvst.14.3.8

Includes: Supplemental Content

Letters to the Editor March 2025

The Predictive and Explanatory Power of the Contrast Theory of Myopia

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Jay Neitz; Maureen Neitz
TAGS: myopia
Trans. Vis. Sci. Tech.. 2025; 14(3):11. https://doi.org/10.1167/tvst.14.3.11

Public Health March 2025

Visual Deficits in Type 2 Diabetes Mellitus Without Retinopathy: From Retinal Structure to Higher-Level Visual Functions

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Sha Luo; Lin Xia; Yue Wang; Yong Tang; Jiong Dong; Rong Liu; Lixia Feng
TAGS: diabetes mellitus, diabetes mellitus, type 2, retina, retinal diseases, vision, vision disorders
Trans. Vis. Sci. Tech.. 2025; 14(3):10. https://doi.org/10.1167/tvst.14.3.10

Includes: Supplemental Content

Erratum March 2025

Erratum in: Accelerometer-Measured Daily Behaviors That Mediate the Association Between Refractive Status and Depressive Disorders

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Trans. Vis. Sci. Tech.. 2025; 14(3):7. https://doi.org/10.1167/tvst.14.3.7

Review March 2025

Advances in OCT Angiography

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Tristan T. Hormel; David Huang; Yali Jia
TAGS: angiogram, artifacts, diagnostic imaging, deep learning, fluid flow, body tissue
Trans. Vis. Sci. Tech.. 2025; 14(3):6. https://doi.org/10.1167/tvst.14.3.6

Retina March 2025

Application of 3D MRI and SS-OCT/OCTA in Assessment of Posterior Scleral Contraction for Myopic Traction Maculopathy

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Danyang Yu; Di Wu; Haoru Li; Hua Rong; Qing He; Xia Zhang; He Xu; Mengdi Chai; Yifan Zhou; Ruihua Wei
TAGS: 3d mri, myopic foveoschisis, sclera, surgical procedures, operative, preoperative care, postoperative care, retinoschisis
Trans. Vis. Sci. Tech.. 2025; 14(3):5. https://doi.org/10.1167/tvst.14.3.5

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High-Performance, Low-Cost Optical Coherence Tomography System Using a Jetson Orin Nano for Real-Time Control and Image Processing

Comparing the Performance of Stress-Strain Index Versions 1 and 2 in Normal and Keratoconus Patients

Regional Biomechanical Weakening in Keratoconus Corneas Detected by In Vivo High-Frequency Ultrasound Elastography

Carboxyamidotriazole Complexed to PLGA Is Safe, Effective, and Durable in Models of Neovascular Retinal Disease

Evaluation of Suprachoroidal Injection in Cadaveric and Preclinical Models

Corneal Layer Segmentation in Healthy and Pathological Eyes: A Joint Super-Resolution Generative Adversarial Network and Adaptive Graph Theory Approach

Enhanced Riboflavin Stromal Delivery Using Microchannel-Assisted Iontophoresis for Corneal Crosslinking

Artificial Intelligence–Driven Detection of LASIK Using Corneal Optical Coherence Tomography Maps

Quantifying the Progression of Stargardt Disease in Double-Null ABCA4 Carriers Using Fundus Autofluorescence Imaging

The Association of Social Determinants of Health on Monitoring for Disease Progression Among Patients With Primary Open-Angle Glaucoma

The Combination of Retinal Neurovascular Unit Changes With Carotid Artery Stenosis Enhances the Prediction of Ischemic Stroke

Retinal Microvascular Biomarker Assessment With Automated Algorithm and Semiautomated Software in the Montrachet Dataset

Quantitative Evaluation of Changes in Retinal and Choroidal Blood Flow Following Strabismus Surgery

Measurement of Aqueous Humor Viscosity in an Experimental Rabbit Model With Corneal Neovascularization

The Peripheral Defocus Designed Spectacle Lenses Might Increase Astigmatism in Myopic Children

The Predictive and Explanatory Power of the Contrast Theory of Myopia

Visual Deficits in Type 2 Diabetes Mellitus Without Retinopathy: From Retinal Structure to Higher-Level Visual Functions

Erratum in: Accelerometer-Measured Daily Behaviors That Mediate the Association Between Refractive Status and Depressive Disorders

Advances in OCT Angiography

Application of 3D MRI and SS-OCT/OCTA in Assessment of Posterior Scleral Contraction for Myopic Traction Maculopathy

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