Translational Research

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Retina December 2024

Assessing Contrast Sensitivity Function in CRB1 -Retinopathies: Exploring Child-Friendly Measures of Visual Function

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Ana Catalina Rodriguez-Martinez; Vijay K. Tailor-Hamblin; Michael D. Crossland; Bethany E. Higgins; Enzo Blindow; Tessa M. Dekker; John A. Greenwood; Robert H. Henderson; Pete R. Jones; Mariya Moosajee
TAGS: child, contrast sensitivity, retinal diseases, vision, visual acuity, cohort studies, spatial frequency
Trans. Vis. Sci. Tech.. 2024; 13(12):33. https://doi.org/10.1167/tvst.13.12.33

Retina December 2024

Phase 1b Dose Escalation Study of Sozinibercept Inhibition of Vascular Endothelial Growth Factors C and D With Aflibercept for Diabetic Macular Edema

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David S. Boyer; Nathan C. Steinle; Joel A. Pearlman; Cameron M. Stone; Courtney Crawford; Sunil Gupta; Pravin U. Dugel; Megan E. Baldwin; Ian M. Leitch
TAGS: aflibercept, diabetic macular edema, vascular endothelial growth factor a, vascular endothelial growth factor c, vascular endothelial growth factors
Trans. Vis. Sci. Tech.. 2024; 13(12):32. https://doi.org/10.1167/tvst.13.12.32

Artificial Intelligence December 2024

A Deep Learning Network for Accurate Retinal Multidisease Diagnosis Using Multiview Fusion of En Face and B-Scan Images: A Multicenter Study

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Chubin Ou; Xifei Wei; Lin An; Jia Qin; Min Zhu; Mei Jin; Xiangbin Kong
TAGS: deep learning, face, multicenter studies
Trans. Vis. Sci. Tech.. 2024; 13(12):31. https://doi.org/10.1167/tvst.13.12.31

Includes: Supplemental Content

Neuro-ophthalmology December 2024

Objective Visual Acuity Estimates in Amblyopia Are More Accurate With Optotype-Based P300 Than With VEP Measurements

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Akshara V. Gopiswaminathan; Julia Haldina; Khaldoon O. Al-Nosairy; Céline Z. Duval; Francie H. Stolle; Michael B. Hoffmann; Sven P. Heinrich
TAGS: amblyopia, evoked potentials, visual, visual acuity, eye
Trans. Vis. Sci. Tech.. 2024; 13(12):30. https://doi.org/10.1167/tvst.13.12.30

Includes: Supplemental Content

Cornea & External Disease December 2024

In Vivo Contactless, Cellular-Resolution Imaging of the Healthy and Pathological Human Limbus With 250-kHz Point-Scanning SD-OCT

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Kostadinka Bizheva; Zohreh Hosseinaee; Kirsten Carter; Denise Hileeto; Brian G. Ballios; Luigina Sorbara; Hall F. Chew
TAGS: body tissue, diagnostic imaging, spectral domain-optical coherence tomography, eye, cicatrix
Trans. Vis. Sci. Tech.. 2024; 13(12):29. https://doi.org/10.1167/tvst.13.12.29

Perspective December 2024

Inherited Retinal Degenerations and Non-Neovascular Age-Related Macular Degeneration: Progress and Unmet Needs

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Jacque L. Duncan; Angela Bowman; Amy Laster; Claire Gelfman; David G. Birch; Shannon E. Boye; Stephen P. Daiger; Lucian del Priore; Donald J. Zack; James T. Handa; the Foundation Fighting Blindness Scientific Advisory Board
TAGS: age-related macular degeneration, genes, genetics, retinal degeneration, disease progression, gene therapy, vision, medical management, blindness
Trans. Vis. Sci. Tech.. 2024; 13(12):28. https://doi.org/10.1167/tvst.13.12.28

Retina December 2024

Clinically Meaningful Change Estimates for the National Eye Institute Visual Function Questionnaire-25 in Patients With Diabetic Macular Edema

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Neil Bressler; Zdenka Haskova; Audrey Kapre; Brittany Gentile
TAGS: diabetic macular edema, eye, questionnaires, vision, visual acuity
Trans. Vis. Sci. Tech.. 2024; 13(12):27. https://doi.org/10.1167/tvst.13.12.27

Includes: Supplemental Content

Retina December 2024

Comparing the Thin Plate Spline and Gaussian Interpolation Methods in Generating Hill of Visions for X-Linked Retinitis Pigmentosa Patients

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A. Yasin Alibhai; Lucas R. De Pretto; Antonio Yaghy; Kwang Min Woo; Naira Raquel dos Santos Xilau; Haleema Siddiqui; Christopher A. Pandiscio; Alex Homer; Darin Curtiss; Nadia K. Waheed
TAGS: retinitis pigmentosa, vision, x-linked inheritance, visual fields
Trans. Vis. Sci. Tech.. 2024; 13(12):26. https://doi.org/10.1167/tvst.13.12.26

Lens December 2024

Disruption of the Enterococcus faecalis– Induced Biofilm on the Intraocular Lens Using Bacteriophages

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Tatsuma Kishimoto; Ken Fukuda; Waka Ishida; Aozora Kuwana; Daisuke Todokoro; Jumpei Uchiyama; Shigenobu Matsuzaki; Kenji Yamashiro
TAGS: bacteriophages, biofilms, intraocular lens implant device, vancomycin, enterococcus faecalis, bacteria, intraocular lens implantation procedure
Trans. Vis. Sci. Tech.. 2024; 13(12):25. https://doi.org/10.1167/tvst.13.12.25

Neuro-ophthalmology December 2024

Refining Flash Visual Evoked Potential Analysis in Rats: A Novel Approach Using Bilateral Epidural Electrodes

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Kwang Min Woo; Yan Guo; Zara Mehrabian; Neil R. Miller; Steven L. Bernstein
TAGS: bone screws, evoked potentials, visual, eye, rats, vision, waveforms, visual acuity, needles, significance, implantation procedure
Trans. Vis. Sci. Tech.. 2024; 13(12):24. https://doi.org/10.1167/tvst.13.12.24

Methods December 2024

Using Hierarchical Bayesian Modeling to Enhance Statistical Inference on Contrast Sensitivity

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Yukai Zhao; Luis Andres Lesmes; Michael Dorr; Zhong-Lin Lu
TAGS: carotid sinus syncope, churg-strauss syndrome, contrast sensitivity, inference, luminance, datasets
Trans. Vis. Sci. Tech.. 2024; 13(12):17. https://doi.org/10.1167/tvst.13.12.17

Includes: Supplemental Content

Retina December 2024

Multi-Omics Integration With Machine Learning Identified Early Diabetic Retinopathy, Diabetic Macula Edema and Anti-VEGF Treatment Response

PDF

Yuhui Pang; Chaokun Luo; Qingruo Zhang; Xiongze Zhang; Nanying Liao; Yuying Ji; Lan Mi; Yuhong Gan; Yongyue Su; Feng Wen; Hui Chen
TAGS: anti-vascular endothelial growth factor therapy, diabetes mellitus, diabetic retinopathy, edema, machine learning, multiomics, macula lutea, hypertension, nonproliferative diabetic retinopathy, metabolomics
Trans. Vis. Sci. Tech.. 2024; 13(12):23. https://doi.org/10.1167/tvst.13.12.23

Includes: Supplemental Content

Cornea & External Disease December 2024

Corneal Confocal Microscopy Identifies and Differentiates Patients With Multiple Sclerosis and Epilepsy

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Ioannis N. Petropoulos; Kareem Essam Aly; Shaikha Al-Thani; Georgios Ponirakis; Hoda Gad; Adnan Khan; Beatriz Canibano; Dirk Deleu; Naveed Akhtar; Gayane Melikyan; Boulenouar Mesraoua; Maria Siddiqi; Jon Perkins; Novsheen Mir; Reny Francis; Abdul Salam; Ahmed El-Sotouhy; Surjith Vattoth; Ahmed Own; Saadat Kamran; Rayaz A. Malik
TAGS: cornea, epilepsy, microscopy, confocal, multiple sclerosis, nerve degeneration
Trans. Vis. Sci. Tech.. 2024; 13(12):22. https://doi.org/10.1167/tvst.13.12.22

Glaucoma December 2024

A Pattern-Based OCT Metric for Glaucoma Detection

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Donald C. Hood; Sol La Bruna; Mary Durbin; Chris Lee; Anya Guzman; Tayna Gebhardt; Yujia Wang; Arin L. Stowman; Carlos Gustavo De Moraes; Michael Chaglasian; Emmanouil Tsamis
TAGS: eye, glaucoma, cohort studies
Trans. Vis. Sci. Tech.. 2024; 13(12):21. https://doi.org/10.1167/tvst.13.12.21

Includes: Supplemental Content

Author Response to Letter December 2024

Author Response: The Distribution of True Visual Field Progression Rates in Glaucoma

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Giovanni Montesano; David P. Crabb; David M. Wright; Alessandro Rabiolo; Giovanni Ometto; David F. Garway-Heath

Trans. Vis. Sci. Tech.. 2024; 13(12):20. https://doi.org/10.1167/tvst.13.12.20

Retina December 2024

Band Visibility in High-Resolution Optical Coherence Tomography Assessed With a Custom Review Tool and Updated, Histology-Derived Nomenclature

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Lukas Goerdt; Thomas A. Swain; Deepayan Kar; Gerald McGwin; Andreas Berlin; Mark E. Clark; Cynthia Owsley; Kenneth R. Sloan; Christine A. Curcio
TAGS: eye, histology, optical coherence tomography, retina, software, reliability, volume electron microscopy, diagnostic imaging
Trans. Vis. Sci. Tech.. 2024; 13(12):19. https://doi.org/10.1167/tvst.13.12.19

Includes: Multimedia, Supplemental Content

Cornea & External Disease December 2024

The Effect of Terpinen-4-ol on Human Corneal Epithelium

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Joo-Hee Park; Choul Yong Park
TAGS: cell survival, cornea, corneal epithelium, epithelium, toxic effect, corneal epithelial cells, mass or substance concentration per volume, cell count, eyelid scrub, immunocytochemistry
Trans. Vis. Sci. Tech.. 2024; 13(12):18. https://doi.org/10.1167/tvst.13.12.18

Includes: Supplemental Content

Cornea & External Disease December 2024

Eye-Rubbing Detection Tool Using Artificial Intelligence on a Smartwatch in the Management of Keratoconus

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Ines Drira; Ayoub Louja; Layth Sliman; Vincent Soler; Maha Noor; Abdellah Jamali; Pierre Fournie
TAGS: artificial intelligence, eye, keratoconus, smartwatches, training, machine learning
Trans. Vis. Sci. Tech.. 2024; 13(12):16. https://doi.org/10.1167/tvst.13.12.16

Artificial Intelligence December 2024

Archetypal Analysis Reveals Consistent Visual Field Patterns for Stimulus Sizes III and V in Glaucoma and NAION

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David Szanto; Michael Wall; Luke X. Chong; Brian Woods; Tobias Elze; Jui-Kai Wang; Mona Garvin; Randy Kardon; Mark J. Kupersmith
TAGS: glaucoma, nonarteritic anterior ischemic optic neuropathy, visual fields, antithymoglobulin, arterial tortuosity syndrome, periodic paralysis, potassium-sensitive cardiodysrhythmic type
Trans. Vis. Sci. Tech.. 2024; 13(12):15. https://doi.org/10.1167/tvst.13.12.15

Includes: Supplemental Content

Retina December 2024

Choroidal and Choriocapillaris OCT-A Analysis in Patients Affected by Active Central Serous Chorioretinopathy

PDF

Maria Ludovica Ruggeri; Marzia Passamonti; Alberto Quarta; Olgers Koci; Annamaria Porreca; Marta Di Nicola; Lucio Zeppa; Rodolfo Mastropasqua; Lisa Toto
TAGS: central serous chorioretinopathy
Trans. Vis. Sci. Tech.. 2024; 13(12):14. https://doi.org/10.1167/tvst.13.12.14

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Assessing Contrast Sensitivity Function in CRB1 -Retinopathies: Exploring Child-Friendly Measures of Visual Function

Phase 1b Dose Escalation Study of Sozinibercept Inhibition of Vascular Endothelial Growth Factors C and D With Aflibercept for Diabetic Macular Edema

A Deep Learning Network for Accurate Retinal Multidisease Diagnosis Using Multiview Fusion of En Face and B-Scan Images: A Multicenter Study

Objective Visual Acuity Estimates in Amblyopia Are More Accurate With Optotype-Based P300 Than With VEP Measurements

In Vivo Contactless, Cellular-Resolution Imaging of the Healthy and Pathological Human Limbus With 250-kHz Point-Scanning SD-OCT

Inherited Retinal Degenerations and Non-Neovascular Age-Related Macular Degeneration: Progress and Unmet Needs

Clinically Meaningful Change Estimates for the National Eye Institute Visual Function Questionnaire-25 in Patients With Diabetic Macular Edema

Comparing the Thin Plate Spline and Gaussian Interpolation Methods in Generating Hill of Visions for X-Linked Retinitis Pigmentosa Patients

Disruption of the Enterococcus faecalis– Induced Biofilm on the Intraocular Lens Using Bacteriophages

Refining Flash Visual Evoked Potential Analysis in Rats: A Novel Approach Using Bilateral Epidural Electrodes

Using Hierarchical Bayesian Modeling to Enhance Statistical Inference on Contrast Sensitivity

Multi-Omics Integration With Machine Learning Identified Early Diabetic Retinopathy, Diabetic Macula Edema and Anti-VEGF Treatment Response

Corneal Confocal Microscopy Identifies and Differentiates Patients With Multiple Sclerosis and Epilepsy

A Pattern-Based OCT Metric for Glaucoma Detection

Author Response: The Distribution of True Visual Field Progression Rates in Glaucoma

Band Visibility in High-Resolution Optical Coherence Tomography Assessed With a Custom Review Tool and Updated, Histology-Derived Nomenclature

The Effect of Terpinen-4-ol on Human Corneal Epithelium

Eye-Rubbing Detection Tool Using Artificial Intelligence on a Smartwatch in the Management of Keratoconus

Archetypal Analysis Reveals Consistent Visual Field Patterns for Stimulus Sizes III and V in Glaucoma and NAION

Choroidal and Choriocapillaris OCT-A Analysis in Patients Affected by Active Central Serous Chorioretinopathy

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